Detailed information NTG0084773

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: K5606_RS13105
• Genome accession: NZ_AP024318
• Coordinates: 2650994..2651881 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain S36
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2645994..2656881

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K5606_RS13075	-	2646003..2646095 (+)	93	WP_031774855.1	hypothetical protein	-
K5606_RS13080 (S36TP_24650)	-	2646203..2646700 (-)	498	WP_001065267.1	glutathione peroxidase	-
K5606_RS13085 (S36TP_24660)	-	2646710..2646970 (-)	261	WP_014937088.1	hypothetical protein	-
K5606_RS13090	-	2647352..2647465 (-)	114	WP_014937089.1	hypothetical protein	-
K5606_RS13095 (S36TP_24670)	-	2648134..2650134 (-)	2001	WP_000776741.1	ABC transporter permease	-
K5606_RS13100 (S36TP_24680)	-	2650131..2650886 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
K5606_RS13105 (S36TP_24690)	braS	2650994..2651881 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
K5606_RS13110 (S36TP_24700)	braR	2651892..2652557 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
K5606_RS13115 (S36TP_24710)	-	2652583..2652783 (-)	201	WP_000604731.1	hypothetical protein	-
K5606_RS13120 (S36TP_24720)	-	2652981..2654405 (+)	1425	WP_000953736.1	alkaline phosphatase	-
K5606_RS13890	-	2654465..2654566 (-)	102	WP_000731972.1	SE2200 family small protein	-
K5606_RS13130 (S36TP_24730)	-	2654688..2655143 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
K5606_RS13135 (S36TP_24740)	-	2655387..2656148 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=84773 K5606_RS13105 WP_000143420.1 2650994..2651881(-) (braS) [Staphylococcus aureus strain S36]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=84773 K5606_RS13105 WP_000143420.1 2650994..2651881(-) (braS) [Staphylococcus aureus strain S36]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993