Detailed information NTG0847451

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLA22_RS10765
• Genome accession: NZ_CP128421
• Coordinates: 2120973..2122004 (-)
• Length: 343 a.a.
• NCBI ID: WP_396418192.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain A.2.2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2115973..2127004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLA22_RS10735 (LLA22_10795)	-	2117176..2117673 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLA22_RS10740 (LLA22_10800)	-	2117660..2117869 (-)	210	WP_011677212.1	hypothetical protein	-
LLA22_RS10745 (LLA22_10805)	-	2117866..2118090 (-)	225	WP_021211256.1	hypothetical protein	-
LLA22_RS10750 (LLA22_10810)	-	2118157..2119047 (+)	891	WP_015082946.1	IS982 family transposase	-
LLA22_RS10755 (LLA22_10815)	kwcM	2119154..2120473 (-)	1320	WP_015082947.1	KxxxW cyclic peptide radical SAM maturase	-
LLA22_RS10760 (LLA22_10820)	-	2120541..2120654 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLA22_RS10765 (LLA22_10825)	sepM	2120973..2122004 (-)	1032	WP_396418192.1	SepM family pheromone-processing serine protease	Regulator
LLA22_RS10770 (LLA22_10830)	coaD	2121988..2122488 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLA22_RS10775 (LLA22_10835)	rsmD	2122536..2123075 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLA22_RS10780 (LLA22_10840)	-	2123245..2124465 (-)	1221	WP_011677216.1	MFS transporter	-
LLA22_RS10785 (LLA22_10845)	lmrP	2124545..2125771 (-)	1227	Protein_2094	multidrug efflux MFS transporter LmrP	-
LLA22_RS10790 (LLA22_10850)	-	2125959..2126453 (+)	495	WP_015082948.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37412.05 Da
• Isoelectric Point: 9.8499

>NTDB_id=847451 LLA22_RS10765 WP_396418192.1 2120973..2122004(-) (sepM) [Lactococcus cremoris strain A.2.2]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTLNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=847451 LLA22_RS10765 WP_396418192.1 2120973..2122004(-) (sepM) [Lactococcus cremoris strain A.2.2]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACACTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (135-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (237-339)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49