Detailed information NTG0847216

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QTN91_RS11440
• Genome accession: NZ_CP128389
• Coordinates: 2377466..2378509 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 21-024
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2372466..2383509

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTN91_RS11410 (QTN91_11410)	-	2373081..2373191 (+)	111	WP_014937049.1	hypothetical protein	-
QTN91_RS11415 (QTN91_11415)	-	2373220..2373633 (+)	414	WP_025174370.1	hypothetical protein	-
QTN91_RS11420 (QTN91_11420)	-	2373822..2374808 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
QTN91_RS11425 (QTN91_11425)	map	2375392..2376150 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
QTN91_RS11430 (QTN91_11430)	-	2376367..2376753 (+)	387	WP_001110182.1	hypothetical protein	-
QTN91_RS11435 (QTN91_11435)	liaF	2376768..2377469 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QTN91_RS11440 (QTN91_11440)	vraS	2377466..2378509 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QTN91_RS11445 (QTN91_11445)	vraR	2378499..2379128 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QTN91_RS11450 (QTN91_11450)	-	2379241..2380458 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
QTN91_RS11455 (QTN91_11455)	-	2380736..2381011 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QTN91_RS11460 (QTN91_11460)	-	2381018..2381482 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QTN91_RS11465 (QTN91_11465)	-	2381629..2381829 (+)	201	WP_000180460.1	DUF1128 family protein	-
QTN91_RS11470 (QTN91_11470)	-	2381832..2383088 (+)	1257	WP_074347694.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=847216 QTN91_RS11440 WP_001017131.1 2377466..2378509(+) (vraS) [Staphylococcus aureus strain 21-024]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=847216 QTN91_RS11440 WP_001017131.1 2377466..2378509(+) (vraS) [Staphylococcus aureus strain 21-024]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1