Detailed information NTG0084685

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: K5605_RS13660
• Genome accession: NZ_AP024313
• Coordinates: 2744164..2745051 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain N1195
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2739164..2750051

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K5605_RS13630	-	2739173..2739265 (+)	93	WP_031774855.1	hypothetical protein	-
K5605_RS13635 (N1195TP_25820)	-	2739373..2739870 (-)	498	Protein_2670	glutathione peroxidase	-
K5605_RS13640 (N1195TP_25830)	-	2739880..2740140 (-)	261	WP_014937088.1	hypothetical protein	-
K5605_RS13645	-	2740522..2740635 (-)	114	WP_014937089.1	hypothetical protein	-
K5605_RS13650 (N1195TP_25840)	-	2741304..2743304 (-)	2001	WP_000776741.1	ABC transporter permease	-
K5605_RS13655 (N1195TP_25850)	-	2743301..2744056 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
K5605_RS13660 (N1195TP_25860)	braS	2744164..2745051 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
K5605_RS13665 (N1195TP_25870)	braR	2745062..2745727 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
K5605_RS13670 (N1195TP_25880)	-	2745753..2745953 (-)	201	WP_000604731.1	hypothetical protein	-
K5605_RS13675 (N1195TP_25890)	-	2746151..2747575 (+)	1425	WP_000953736.1	alkaline phosphatase	-
K5605_RS14335	-	2747635..2747736 (-)	102	WP_000731972.1	SE2200 family small protein	-
K5605_RS13685 (N1195TP_25900)	-	2747858..2748313 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
K5605_RS13690 (N1195TP_25910)	-	2748557..2749318 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=84685 K5605_RS13660 WP_000143420.1 2744164..2745051(-) (braS) [Staphylococcus aureus strain N1195]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=84685 K5605_RS13660 WP_000143420.1 2744164..2745051(-) (braS) [Staphylococcus aureus strain N1195]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993