Detailed information NTG0846594

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V3435_RS02360
• Genome accession: NZ_CP144270
• Coordinates: 467221..469830 (+)
• Length: 869 a.a.
• NCBI ID: WP_000353948.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain LA52
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 462221..474830

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V3435_RS02345 (V3435_02345)	-	463360..464184 (-)	825	WP_001182436.1	Cof-type HAD-IIB family hydrolase	-
V3435_RS02350 (V3435_02350)	-	464298..464606 (+)	309	WP_000390575.1	metal-sulfur cluster assembly factor	-
V3435_RS02355 (V3435_02355)	-	465204..467018 (+)	1815	WP_001044238.1	acyltransferase family protein	-
V3435_RS02360 (V3435_02360)	clpC	467221..469830 (+)	2610	WP_000353948.1	ATP-dependent chaperone ClpB	Regulator
V3435_RS02365 (V3435_02365)	-	469889..470758 (-)	870	WP_001047061.1	LysR family transcriptional regulator	-
V3435_RS02370 (V3435_02370)	-	470889..471404 (+)	516	WP_000700886.1	YbhB/YbcL family Raf kinase inhibitor-like protein	-
V3435_RS02375 (V3435_02375)	-	471715..472149 (+)	435	WP_000769695.1	MAP domain-containing protein	-
V3435_RS02380 (V3435_02380)	-	472406..472591 (-)	186	WP_000682089.1	YjzD family protein	-
V3435_RS02385 (V3435_02385)	-	472886..473827 (+)	942	WP_001100526.1	beta-ketoacyl-ACP synthase III	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98344.54 Da
• Isoelectric Point: 4.7024

>NTDB_id=846594 V3435_RS02360 WP_000353948.1 467221..469830(+) (clpC) [Staphylococcus aureus strain LA52]
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQ
YGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELD
LSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYRE
YIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATI
RTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIAKLQEKRAQLDE
NRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETER
EKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSE
YMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIM
TSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIE
VSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE

Nucleotide

• Length: 2610 bp

>NTDB_id=846594 V3435_RS02360 WP_000353948.1 467221..469830(+) (clpC) [Staphylococcus aureus strain LA52]
ATGGATATAAATAAAATGACATATGCTGTTCAAAGTGCTTTACAACAAGCAGTTGAACTGAGTCAGCAACATAAATTACA
AAATATAGAAATTGAGGCAATTTTAAGCGCTGCCTTAAATGAAAGTGAAAGCTTATATAAAAGTATTTTAGAACGAGCAA
ATATTGAGGTAGATCAATTAAACAAAGCTTATGAAGACAAACTAAACACGTATGCATCTGTAGAAGGTGACAATATACAA
TATGGTCAATATATTAGCCAACAAGCAAACCAATTGATAACTAAGGCTGAATCATACATGAAAGAATATGAAGATGAATA
TATTTCAATGGAGCATATTTTACGTTCGGCAATGGACATTGATCAAACAACAAAACATTATATAAATAATAAAGTAGAAG
TTATCAAAGAAATTATTAAAAAAGTAAGAGGGGGAAATCACGTGACATCACAAAATCCTGAAGTTAATTACGAAGCATTA
GCTAAATATGGCCGCGACTTAGTAGAAGAAGTTAGACAAGGTAAAATGGATCCTGTTATAGGAAGAGATGAAGAAATTCG
AAATACGATTCGTATTTTAAGTCGTAAAACTAAAAACAACCCTGTGCTCATTGGTGAACCAGGTGTTGGTAAAACTGCAA
TTGTTGAAGGATTAGCGCAACGTATAGTTAAGAAAGATGTGCCAGAATCATTATTAGATAAAACTGTTTTTGAGTTAGAT
TTAAGCGCATTAGTAGCGGGCGCTAAATATCGTGGTGAATTTGAAGAGAGATTAAAAGCAGTCCTAAAAGAAGTTAAAGA
GTCTGATGGTAGAATTATATTATTTATTGATGAAATCCATATGCTTGTAGGTGCTGGTAAAACAGATGGTGCCATGGATG
CAGGCAACATGCTAAAACCAATGTTAGCACGAGGAGAGTTACATTGTATTGGTGCAACAACTTTAAATGAATATCGAGAA
TATATTGAAAAAGATTCGGCATTAGAGCGTCGTTTCCAAAAAGTAGCAGTTAGTGAGCCTGATGTTGAAGATACAATTTC
AATTTTACGTGGTTTAAAAGAACGATATGAAGTGTATCATGGTGTGCGTATTCAAGATAGAGCCTTAGTTGCTGCCGCTG
AATTGTCTGATCGTTACATCACTGATCGTTTTTTACCAGATAAAGCGATTGATTTAGTTGACCAAGCATGTGCAACAATT
CGTACGGAAATGGGATCAAATCCAACTGAATTGGATCAAGTTAATAGACGTGTCATGCAATTAGAAATTGAAGAAAGCGC
ACTTAAAAATGAATCTGACAATGCGAGCAAACAGAGATTACAAGAACTACAAGAAGAGCTTGCCAATGAAAAAGAGAAAC
AAGCAGCACTTCAATCTCGTGTAGAATCAGAAAAAGAAAAAATAGCAAAGTTACAAGAAAAACGTGCGCAATTAGATGAA
AATAGACAAGCGTTGGAAGATGCACAAACAAATAACAATTTAGAAAAAGCTGCTGAACTACAATATGGAACAATTCCTCA
ATTGGAAAAAGAACTTAGAGAATTAGAGGATAATTTCCAAGATGAGCAAGGTGAAGATACAGATCGAATGATTCGTGAAG
TTGTAACAGACGAAGAAATTGGCGATATTGTCAGCCAATGGACAGGCATACCAGTTTCAAAATTAGTTGAAACAGAACGT
GAAAAATTACTTCACTTAAGTGATATCTTGCATAAACGTGTTGTAGGTCAAGATAAAGCGGTTGACCTGGTTTCAGATGC
AGTAGTTAGAGCTAGAGCAGGTATTAAAGATCCAAACAGACCTATTGGTAGTTTCTTATTCCTAGGTCCAACTGGGGTAG
GTAAAACTGAATTAGCTAAATCATTAGCTGCATCATTATTTGATTCTGAAAAACATATGATTCGTATTGATATGAGTGAA
TATATGGAAAAACATGCAGTATCAAGATTGATTGGGGCACCTCCAGGATATATTGGACATGATGAAGGGGGTCAATTAAC
TGAAGCGGTTCGTCGTAATCCATACTCAGTTATTTTATTAGATGAGGTTGAAAAAGCGCATACTGACGTCTTTAATGTAT
TATTGCAAATTTTAGATGAAGGCCGTTTAACTGATTCTAAAGGACGTAGCGTTGATTTTAAAAATACTATTATTATTATG
ACAAGTAATATTGGATCTCAAGTTTTACTAGAAAACGTAAAAGAGACTGGTGAAATTACAGAATCAACAGAAAAAGCTGT
TATGACAAGTTTAAATGCATATTTCAAACCAGAAATTTTGAATCGTATGGATGACATCGTATTATTTAAACCTTTATCTA
TTGATGACATGAGTATGATTGTAGACAAAATATTAACGCAATTAAATATAAGATTACTAGAACAACGAATCTCAATTGAA
GTTTCTGATGATGCTAAAGCTTGGCTAGGTCAAGAGGCTTATGAACCTCAATACGGTGCAAGACCATTAAAACGTTTTGT
ACAACGCCAAATTGAAACACCATTAGCACGTATGATGATTAAAGAGGGATTCCCAGAAGGTACAACTATTAAAGTTAATT
TAAATTCAGACAATAACTTAACGTTTAATGTTGAAAAAATTCATGAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (772-852)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-766)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-121)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• ATPase family associated with various cellular activities (AAA) (AAA) (202-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.009	99.885	0.44
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.091	100	0.405
clpC	Lactococcus lactis subsp. cremoris KW2	47.475	79.747	0.379