Detailed information NTG0084640

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ST1232TP_RS13685
• Genome accession: NZ_AP024311
• Coordinates: 2748142..2749029 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain THI2018-120
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2743142..2754029

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST1232TP_RS13655	-	2743151..2743243 (+)	93	WP_031774855.1	hypothetical protein	-
ST1232TP_RS13660 (THI2018120TP_25860)	-	2743351..2743848 (-)	498	Protein_2675	glutathione peroxidase	-
ST1232TP_RS13665 (THI2018120TP_25870)	-	2743858..2744118 (-)	261	WP_014937088.1	hypothetical protein	-
ST1232TP_RS13670	-	2744500..2744613 (-)	114	WP_014937089.1	hypothetical protein	-
ST1232TP_RS13675 (THI2018120TP_25880)	-	2745282..2747282 (-)	2001	WP_000776741.1	ABC transporter permease	-
ST1232TP_RS13680 (THI2018120TP_25890)	-	2747279..2748034 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ST1232TP_RS13685 (THI2018120TP_25900)	braS	2748142..2749029 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ST1232TP_RS13690 (THI2018120TP_25910)	braR	2749040..2749705 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ST1232TP_RS13695 (THI2018120TP_25920)	-	2749731..2749931 (-)	201	WP_000604731.1	hypothetical protein	-
ST1232TP_RS13700 (THI2018120TP_25930)	-	2750129..2751553 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ST1232TP_RS14360	-	2751613..2751714 (-)	102	WP_000731972.1	SE2200 family small protein	-
ST1232TP_RS13710 (THI2018120TP_25940)	-	2751836..2752291 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ST1232TP_RS13715 (THI2018120TP_25950)	-	2752535..2753296 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=84640 ST1232TP_RS13685 WP_000143420.1 2748142..2749029(-) (braS) [Staphylococcus aureus strain THI2018-120]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=84640 ST1232TP_RS13685 WP_000143420.1 2748142..2749029(-) (braS) [Staphylococcus aureus strain THI2018-120]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993