Detailed information NTG0845482

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V2189_RS21710
• Genome accession: NZ_CP143908
• Coordinates: 4644830..4647394 (-)
• Length: 854 a.a.
• NCBI ID: WP_003094682.1
• Uniprot ID: A0A0H2ZHB4
• Organism: Pseudomonas aeruginosa strain PA4_YH3_36.21_ST773_NDM1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4639830..4652394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V2189_RS21690 (V2189_21690)	tpsA4	4639836..4644116 (+)	4281	WP_033938455.1	two-partner secretion system exoprotein TpsA4	-
V2189_RS21710 (V2189_21710)	clpC	4644830..4647394 (-)	2565	WP_003094682.1	ATP-dependent chaperone ClpB	Regulator
V2189_RS21715 (V2189_21715)	pgeF	4647550..4648278 (-)	729	WP_015503650.1	peptidoglycan editing factor PgeF	-
V2189_RS21720 (V2189_21720)	rluD	4648275..4649237 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
V2189_RS21725 (V2189_21725)	-	4649383..4650408 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
V2189_RS21730 (V2189_21730)	-	4650565..4650810 (+)	246	WP_003102591.1	PP0621 family protein	-
V2189_RS21735 (V2189_21735)	pilS	4650800..4652392 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 95005.65 Da
• Isoelectric Point: 5.1331

>NTDB_id=845482 V2189_RS21710 WP_003094682.1 4644830..4647394(-) (clpC) [Pseudomonas aeruginosa strain PA4_YH3_36.21_ST773_NDM1]
MRIDRLTSKLQLALSDAQSLAVGHDHPAIEPVHLLSALLEQQGGSIKPLLMQVGFDIAALRSGLNKELDALPKIQSPTGD
VNLSQDLARLLNQADRLAQQKGDQFISSELVLLAAMDENTRLGKLLLGQGVSRKALENAVANLRGGEAVNDPNVEESRQA
LDKYTVDMTKRAEEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPDGLKDKRLLAL
DMGALIAGAKFRGEFEERLKAVLNELGKQEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSEEDTIAILRGLKERYEVHHGVSITDGAIIAAAKLSHRYITDRQLPDKAIDLIDEAASR
IRMEIDSKPEELDRLDRRLIQLKIEREALKKEDDEATRKRLAKLEEDIVKLEREYADLEEIWKSEKAEVQGSAQIQQKIE
QAKQEMEAARRKGDLESMARIQYQTIPDLERSLQMVDQHGKTENQLLRNKVTDEEIAEVVSKWTGIPVSKMLEGEREKLL
RMEQELHRRVIGQDEAVVAVSNAVRRSRAGLADPNRPSGSFLFLGPTGVGKTELCKALAEFLFDTEEALVRIDMSEFMEK
HSVARLIGAPPGYVGFEEGGYLTEAIRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRLTDSHGRTVDFRNTVVVMTSNL
GSAQIQELAGDREAQRAAVMDAVNAHFRPEFINRIDEVVVFEPLAREQIAGIAEIQLGRLRKRLAERELSLELSQEALDK
LIAVGFDPVYGARPLKRAIQRWIENPLAQLILAGKFAPGASISAKVEGDEIVFA

Nucleotide

• Length: 2565 bp

>NTDB_id=845482 V2189_RS21710 WP_003094682.1 4644830..4647394(-) (clpC) [Pseudomonas aeruginosa strain PA4_YH3_36.21_ST773_NDM1]
ATGCGAATAGACCGTTTGACCAGCAAGCTGCAACTGGCGCTCTCCGACGCCCAGTCCCTGGCCGTTGGCCATGACCATCC
GGCCATCGAGCCGGTGCACCTGCTTTCCGCCCTGCTCGAGCAGCAAGGCGGTTCGATCAAGCCCCTGCTGATGCAGGTCG
GCTTCGATATCGCCGCCCTGCGCAGCGGCCTCAACAAAGAACTCGACGCGCTGCCGAAGATCCAGAGCCCGACCGGCGAC
GTGAACCTGTCCCAGGATCTCGCACGCCTGCTCAACCAGGCTGACCGCCTGGCCCAGCAGAAGGGCGACCAGTTCATCTC
CAGCGAGCTGGTATTGCTGGCCGCGATGGACGAGAACACCAGGCTCGGCAAGCTGCTGCTCGGCCAGGGCGTGTCGCGCA
AGGCGCTGGAGAATGCCGTGGCCAACCTGCGCGGCGGCGAAGCGGTGAACGACCCGAACGTCGAGGAGTCGCGCCAGGCG
CTGGACAAGTACACCGTCGACATGACCAAGCGCGCCGAGGAAGGCAAGCTCGACCCGGTGATCGGTCGCGACGACGAGAT
CCGCCGGACCATCCAGGTCCTGCAGCGGCGGACCAAGAACAACCCGGTGTTGATCGGCGAACCCGGCGTCGGCAAGACCG
CCATCGTCGAGGGCCTGGCCCAGCGCATCATCAACGGCGAAGTGCCGGACGGCCTCAAGGACAAGCGCCTGCTGGCCCTG
GACATGGGGGCGCTGATCGCCGGTGCCAAGTTCCGCGGCGAGTTCGAGGAACGCCTGAAGGCGGTCCTGAACGAACTGGG
CAAGCAGGAAGGTCGGGTCATCCTGTTCATCGACGAACTGCACACCATGGTCGGCGCCGGCAAGGCGGAAGGCGCCATGG
ACGCCGGCAACATGCTCAAGCCGGCTCTGGCGCGCGGCGAGCTGCACTGCGTCGGTGCTACTACCCTCGACGAGTATCGC
CAGTACATCGAGAAGGATGCTGCGCTGGAGCGCCGCTTCCAGAAGGTGCTGGTGGACGAGCCGAGCGAGGAAGACACCAT
CGCCATCCTCCGTGGCCTCAAGGAACGCTATGAAGTGCACCACGGGGTGAGCATCACCGACGGCGCGATCATCGCCGCGG
CCAAGCTGTCGCACCGCTACATCACCGATCGGCAACTGCCGGACAAGGCCATCGACCTGATCGACGAGGCCGCCAGCCGC
ATCCGCATGGAGATCGACTCCAAGCCGGAGGAACTGGATCGTCTCGACCGTCGCCTGATCCAGCTGAAGATCGAGCGCGA
GGCGCTGAAGAAGGAAGACGACGAAGCCACCAGGAAGCGCCTGGCCAAGCTGGAGGAGGATATCGTCAAGCTCGAGCGCG
AATACGCCGACCTCGAGGAGATCTGGAAGTCCGAGAAGGCCGAGGTACAGGGCTCGGCGCAGATCCAGCAGAAGATCGAG
CAGGCCAAGCAGGAAATGGAGGCGGCGCGGCGCAAGGGCGACCTCGAGAGCATGGCGCGCATCCAGTACCAGACCATCCC
GGACCTGGAGCGCAGCCTGCAGATGGTCGACCAGCACGGCAAGACCGAGAACCAGTTGCTGCGCAACAAGGTGACCGACG
AGGAAATCGCCGAAGTGGTTTCCAAGTGGACCGGTATCCCGGTGTCGAAGATGCTCGAGGGCGAGCGCGAGAAGCTGCTG
CGCATGGAGCAGGAGCTGCATCGGCGAGTGATCGGCCAGGACGAGGCGGTAGTCGCCGTGTCCAACGCCGTGCGCCGTTC
GCGCGCCGGCCTCGCCGATCCGAACCGGCCGAGCGGCTCGTTCCTCTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGT
TGTGCAAGGCGCTTGCCGAGTTCCTCTTCGATACCGAGGAGGCGCTGGTGCGGATCGATATGTCCGAGTTCATGGAGAAA
CACTCGGTGGCCCGCCTGATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAGGAAGGCGGCTACCTGACCGAGGCGATCCG
CCGCAAGCCCTACTCGGTGGTGCTGCTGGACGAGGTGGAGAAGGCCCATCCGGATGTATTCAACATTCTCCTCCAGGTGC
TCGAGGACGGACGCCTGACCGACAGTCACGGGCGTACGGTGGACTTCCGCAACACCGTGGTGGTGATGACCTCCAACCTC
GGTTCGGCGCAGATCCAGGAGCTGGCCGGCGACCGCGAGGCGCAACGTGCCGCAGTGATGGACGCGGTCAATGCGCACTT
CCGTCCGGAATTCATCAACCGGATCGACGAAGTGGTGGTGTTCGAGCCGCTGGCTCGCGAGCAGATCGCCGGCATCGCCG
AGATCCAGCTCGGTCGCCTGCGCAAGCGCCTGGCCGAGCGCGAGCTGAGCCTGGAACTGAGCCAGGAGGCGCTGGACAAG
CTGATCGCCGTCGGCTTCGACCCGGTCTATGGCGCACGCCCGCTGAAGCGGGCCATCCAGCGCTGGATCGAGAACCCGCT
GGCGCAACTGATCCTGGCCGGCAAATTCGCGCCGGGTGCCAGTATCTCGGCGAAGGTGGAAGGCGACGAGATCGTCTTCG
CCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-334)

3D structure

• AlphaFold DB: A0A0H2ZHB4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.391	100	0.493
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.417	100	0.436