Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   L6410_RS08505 Genome accession   NZ_AP024276
Coordinates   1681073..1683316 (+) Length   747 a.a.
NCBI ID   WP_237395323.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SUT-286     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1676073..1688316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6410_RS08480 (SUT286_16510) - 1677009..1677917 (+) 909 WP_024392452.1 neutral zinc metallopeptidase -
  L6410_RS08485 (SUT286_16520) - 1677998..1678849 (-) 852 WP_172055259.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  L6410_RS08490 (SUT286_16530) - 1678978..1679712 (-) 735 WP_172016423.1 amino acid ABC transporter ATP-binding protein -
  L6410_RS08495 (SUT286_16540) - 1679714..1680394 (-) 681 WP_024392449.1 amino acid ABC transporter permease -
  L6410_RS08500 (SUT286_16550) - 1680513..1680743 (-) 231 WP_024392448.1 DUF1797 family protein -
  L6410_RS08505 (SUT286_16560) clpE 1681073..1683316 (+) 2244 WP_237395323.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  L6410_RS08510 (SUT286_16570) - 1683460..1683927 (+) 468 WP_172090000.1 NUDIX hydrolase -
  L6410_RS08515 (SUT286_16580) - 1683974..1684282 (+) 309 WP_024396912.1 DUF1827 family protein -
  L6410_RS08520 (SUT286_16590) ileS 1684604..1687393 (-) 2790 WP_237396771.1 isoleucine--tRNA ligase -
  L6410_RS08525 (SUT286_16600) - 1687404..1687847 (-) 444 WP_024391033.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 83294.72 Da        Isoelectric Point: 5.2838

>NTDB_id=84490 L6410_RS08505 WP_237395323.1 1681073..1683316(+) (clpE) [Streptococcus parasuis strain SUT-286]
MLCTNCKINDATIHLYTNMNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
DQTPPTQAGGGNGGGRFNQPNTGRTQTVPQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQNKYQDYHHVKYSP
EAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKEQATRDEDYEKAAYYRDQIAKYK
EMQKATISEEDIPLITEKEIEAIIEQKTNIPVGELKEKEQSQLIHLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLGNFFTPEFMN
RFDGIIEFQPLTKENLLQIVSLMLEDVNRRLSTNGIRLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLE
NPNEKDLRAVMTNKGTIQIKAQTPKEK

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=84490 L6410_RS08505 WP_237395323.1 1681073..1683316(+) (clpE) [Streptococcus parasuis strain SUT-286]
ATGCTCTGTACAAACTGTAAAATAAATGATGCTACCATTCATCTCTATACAAATATGAATGGCAAACAACAGCAAGTTGA
CCTTTGCCATAATTGTTATCAAATTATGAAAACAGATCCAAATAATGCTATTTTACGTGGCTTAGGGGACTTAACGAATC
CAAACAATATGGATCCATTTAGTGAATTTTTCAATCATTTAGGTGGTTACCCTGGAAATACCCCAGCTGGTAAGAATCGT
GATCAAACACCTCCTACTCAAGCAGGCGGTGGCAACGGTGGTGGTCGATTCAATCAACCCAATACTGGTCGAACCCAAAC
AGTCCCGCAACCAAATGGATTGCTGGAAGAATTTGGGATTAATGTTACTGAGATTGCACGACGTGGAGATATTGACCCCG
TTATCGGACGCGATCAAGAAATCACTCGGGTGATTGAAATTTTGAACCGCCGCACTAAAAACAACCCCGTTCTTATCGGT
GAGCCCGGTGTTGGTAAAACTGCAGTCGTTGAAGGACTAGCACAAAAAATTGTAGACGGGGACGTTCCACATAAACTTCA
AAACAAAGAAGTCATTCGATTAGATGTTGTCAGCCTTGTTCAAGGAACAGGAATCCGAGGTCAATTTGAAGAACGCATGC
AAAAACTCATGGAAGAAATTCGAAACCGACGTGAAGTTATTCTCTTCATTGATGAAATTCATGAGATTGTCGGAGCTGGT
TCTGCAGGAGATGGAAACATGGATGCGGGCAATATTCTAAAACCCGCCCTCGCTCGTGGTGAAATGCAACTGGTCGGTGC
TACTACTTTAAATGAATACCGCATTATTGAAAAAGATGCAGCTCTTGAACGTCGGATGCAACCTGTAAAAGTTGACGAAC
CTAGTGTTGAAGAAACAATCACTATCTTAAAAGGTATTCAGAATAAATACCAAGACTACCACCATGTAAAATATTCCCCT
GAGGCCATTGAAGCTGCGGCCGTATTATCCAACCGCTATATTCAAGACCGATTCTTACCTGACAAAGCGATTGATTTGCT
AGACGAAGCTGGGTCAAAAATGAACTTAACCTTGAACTTCGTGGATCCTAAAGAAATTGACCAACGGTTAATTGATGCCG
AAAATCGTAAAGAACAAGCAACTCGTGATGAAGATTACGAAAAAGCTGCCTATTATCGTGACCAAATTGCTAAATATAAA
GAAATGCAAAAGGCAACGATTAGTGAAGAGGATATTCCTCTCATTACCGAAAAAGAAATCGAAGCCATCATTGAACAAAA
AACAAATATCCCCGTTGGCGAACTGAAAGAAAAAGAACAGTCTCAATTGATACATTTGGCAAGTGATCTCAAAGCGCATG
TCATTGGACAAGACGACGCTGTTGATAAGATTGCAAAAGCAATCCGTCGCAATCGTGTAGGACTTGGAGCACCAAATCGT
CCAATTGGTTCCTTCTTATTCGTAGGACCTACTGGCGTCGGTAAAACAGAATTATCAAAACAATTAGCCATTGAGCTCTT
CGGTTCAGCGGACAGCATGATTCGATTTGATATGTCTGAATATATGGAAAAACACGCAGTTGCAAAACTAGTCGGTGCCC
CTCCTGGATATGTGGGGTATGAAGAAGCTGGCCAACTAACAGAAAAAGTCCGTCGCAATCCATATTCACTCATTCTCCTT
GATGAAGTTGAAAAGGCGCATCCAGATGTGATGCACATGTTCCTACAAGTTCTTGATGACGGTCGACTGACAGATGGACA
AGGGCGAACAGTTAGCTTCAAAGATACCATTATCATTATGACTTCAAATGCTGGTACAGGAAAGGTAGAAGCCAGTGTGG
GATTTGGAGCCGCTATGGAAGGCCGTACACAATCTGTTCTTGGTCAACTCGGTAATTTCTTCACTCCTGAATTTATGAAC
CGCTTCGATGGAATTATTGAATTCCAACCACTCACAAAAGAAAATCTGCTCCAAATTGTCAGTCTCATGCTGGAAGACGT
CAACCGTCGCTTATCTACAAACGGTATTCGACTACATGTGACCGATAAAGTAAAGGAAAAATTAGTTGATCTTGGTTACG
ATCCTAAAATGGGTGCACGTCCCCTTCGCAGGACCATTCAAGACCAAATTGAAGATGCCATTACCGATTTCTATTTAGAG
AATCCTAATGAGAAAGATTTACGAGCTGTCATGACCAATAAAGGCACCATCCAAATCAAAGCTCAAACGCCAAAAGAAAA
ATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-723)

AAA lid domain (AAA_lid_9)

(295-393)

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

83.222

100

0.837
  clpE Streptococcus pneumoniae D39

83.222

100

0.837
  clpE Streptococcus pneumoniae R6

83.222

100

0.837
  clpE Streptococcus pneumoniae TIGR4

83.222

100

0.837
  clpE Streptococcus mutans UA159

82.911

100

0.831
  clpC Lactococcus lactis subsp. cremoris KW2

76.68

97.59

0.748
  clpC Bacillus subtilis subsp. subtilis str. 168

52.167

83.4

0.435
  clpC Streptococcus mutans UA159

47.91

83.266

0.399
  clpC Streptococcus pneumoniae Rx1

47.444

83.802

0.398
  clpC Streptococcus pneumoniae D39

47.444

83.802

0.398
  clpC Streptococcus pneumoniae TIGR4

47.444

83.802

0.398
  clpC Streptococcus thermophilus LMD-9

47.125

83.802

0.395
  clpC Streptococcus thermophilus LMG 18311

46.805

83.802

0.392
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.85

82.865

0.388

Multiple sequence alignment