Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | QQ988_RS00170 | Genome accession | NZ_CP127869 |
| Coordinates | 40350..41711 (-) | Length | 453 a.a. |
| NCBI ID | WP_286096900.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain NG02 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 29835..76750 | 40350..41711 | within | 0 |
Gene organization within MGE regions
Location: 29835..76750
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQ988_RS00120 (QQ988_00120) | - | 29835..30635 (+) | 801 | WP_002447628.1 | MBL fold metallo-hydrolase | - |
| QQ988_RS00125 (QQ988_00125) | rlmH | 31677..32156 (+) | 480 | WP_002458513.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| QQ988_RS00130 (QQ988_00130) | - | 32877..34268 (+) | 1392 | WP_049415494.1 | hypothetical protein | - |
| QQ988_RS00135 (QQ988_00135) | - | 34255..35061 (+) | 807 | WP_049415496.1 | hypothetical protein | - |
| QQ988_RS00140 (QQ988_00140) | - | 35058..35840 (-) | 783 | WP_049415498.1 | site-specific DNA-methyltransferase | - |
| QQ988_RS00145 (QQ988_00145) | - | 35830..36627 (-) | 798 | WP_197682124.1 | site-specific DNA-methyltransferase | - |
| QQ988_RS12050 | - | 36729..36936 (-) | 208 | Protein_27 | hypothetical protein | - |
| QQ988_RS00150 (QQ988_00150) | - | 36950..37447 (-) | 498 | WP_049415501.1 | DUF1643 domain-containing protein | - |
| QQ988_RS00155 (QQ988_00155) | - | 37463..37774 (-) | 312 | WP_049415503.1 | DUF960 family protein | - |
| QQ988_RS00160 (QQ988_00160) | - | 37861..38211 (-) | 351 | WP_002502233.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| QQ988_RS00165 (QQ988_00165) | ccrB | 38731..40353 (-) | 1623 | WP_079335323.1 | recombinase family protein | Machinery gene |
| QQ988_RS00170 (QQ988_00170) | ccrA | 40350..41711 (-) | 1362 | WP_286096900.1 | recombinase family protein | Machinery gene |
| QQ988_RS00175 (QQ988_00175) | - | 41923..43689 (-) | 1767 | WP_049382282.1 | DUF927 domain-containing protein | - |
| QQ988_RS00180 (QQ988_00180) | - | 43689..43982 (-) | 294 | WP_046464617.1 | hypothetical protein | - |
| QQ988_RS00185 (QQ988_00185) | - | 44153..45667 (-) | 1515 | WP_046464618.1 | hypothetical protein | - |
| QQ988_RS00190 (QQ988_00190) | - | 46143..47282 (+) | 1140 | WP_217971187.1 | IS256 family transposase | - |
| QQ988_RS00195 (QQ988_00195) | - | 47339..47731 (+) | 393 | WP_000393259.1 | GNAT family N-acetyltransferase | - |
| QQ988_RS00200 (QQ988_00200) | aph(2'')-Ia | 47732..49171 (+) | 1440 | WP_001028144.1 | aminoglycoside O-phosphotransferase APH(2'')-Ia | - |
| QQ988_RS00205 (QQ988_00205) | - | 49301..50440 (-) | 1140 | WP_217971187.1 | IS256 family transposase | - |
| QQ988_RS00210 (QQ988_00210) | - | 50806..51717 (+) | 912 | WP_046464619.1 | ABC transporter substrate-binding protein | - |
| QQ988_RS00215 (QQ988_00215) | - | 51750..51920 (-) | 171 | WP_155734542.1 | hypothetical protein | - |
| QQ988_RS00220 (QQ988_00220) | - | 51967..52641 (-) | 675 | WP_286096901.1 | IS6 family transposase | - |
| QQ988_RS00225 (QQ988_00225) | - | 52725..53066 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| QQ988_RS00230 (QQ988_00230) | - | 53943..54686 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| QQ988_RS00235 (QQ988_00235) | - | 54783..55211 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| QQ988_RS00240 (QQ988_00240) | mecA | 55257..57266 (-) | 2010 | WP_063852655.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| QQ988_RS00245 (QQ988_00245) | - | 57363..58361 (+) | 999 | WP_053032304.1 | beta-lactam sensor/signal transducer MecR1 | - |
| QQ988_RS00250 (QQ988_00250) | - | 58389..59063 (-) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| QQ988_RS00255 (QQ988_00255) | - | 59107..59661 (+) | 555 | WP_242271952.1 | YheC/YheD family protein | - |
| QQ988_RS00260 (QQ988_00260) | - | 60189..60743 (-) | 555 | Protein_50 | IS3 family transposase | - |
| QQ988_RS12055 | - | 60759..60977 (-) | 219 | WP_141629655.1 | IS3 family transposase | - |
| QQ988_RS00265 (QQ988_00265) | - | 61073..61351 (-) | 279 | WP_080047664.1 | hypothetical protein | - |
| QQ988_RS00270 (QQ988_00270) | - | 61320..61616 (-) | 297 | WP_002493184.1 | transposase | - |
| QQ988_RS00275 (QQ988_00275) | - | 62357..62683 (+) | 327 | WP_000624048.1 | helix-turn-helix transcriptional regulator | - |
| QQ988_RS00280 (QQ988_00280) | - | 62720..63553 (+) | 834 | WP_000694291.1 | CPBP family intramembrane glutamic endopeptidase | - |
| QQ988_RS00285 (QQ988_00285) | - | 63758..63922 (+) | 165 | WP_286096902.1 | DNA mismatch repair protein MutS | - |
| QQ988_RS00290 (QQ988_00290) | - | 64239..65012 (+) | 774 | WP_000998885.1 | hypothetical protein | - |
| QQ988_RS00295 (QQ988_00295) | - | 65250..65594 (-) | 345 | WP_193626407.1 | DUF4870 domain-containing protein | - |
| QQ988_RS00300 (QQ988_00300) | - | 65641..66315 (-) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| QQ988_RS00305 (QQ988_00305) | - | 66370..66861 (-) | 492 | Protein_60 | replication initiator protein A | - |
| QQ988_RS00310 (QQ988_00310) | - | 67376..68068 (+) | 693 | WP_023231271.1 | DUF536 domain-containing protein | - |
| QQ988_RS00315 (QQ988_00315) | - | 68193..68592 (-) | 400 | Protein_62 | VOC family protein | - |
| QQ988_RS00320 (QQ988_00320) | - | 68587..69717 (+) | 1131 | WP_002456255.1 | gamma-glutamyltransferase | - |
| QQ988_RS00325 (QQ988_00325) | - | 69966..70823 (+) | 858 | WP_000162894.1 | YitT family protein | - |
| QQ988_RS00330 (QQ988_00330) | - | 70973..71584 (-) | 612 | WP_000635275.1 | recombinase family protein | - |
| QQ988_RS00335 (QQ988_00335) | - | 72225..74864 (+) | 2640 | WP_196305970.1 | MMPL family transporter | - |
| QQ988_RS00340 (QQ988_00340) | - | 74888..75832 (+) | 945 | WP_206420258.1 | glycine betaine ABC transporter substrate-binding protein | - |
| QQ988_RS00345 (QQ988_00345) | - | 76181..76750 (+) | 570 | WP_206420257.1 | TetR/AcrR family transcriptional regulator | - |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53220.05 Da Isoelectric Point: 9.3190
>NTDB_id=844894 QQ988_RS00170 WP_286096900.1 40350..41711(-) (ccrA) [Staphylococcus epidermidis strain NG02]
MVEAIGYVRQSTLKQQSLATQTSLIMETAKQYGWHNIEFYDDKKTGRNTKRSGYQKMVEMIISGECKVLCCYRLNRLHRN
LKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYR
QGHFVVHEEEAYTVKAVYRWYLQGLGYKKISQHLDNNPKLIPRKPYQVRNILLNPNYCGRVINKYGTFNDLVPSIVDIDT
FEEAQQCRVNKHHKQHISENKLKKLLRCPYCQATLTNLTIKKANHSLHYYVCPRNMNEAYHTCPFKGINALELESKVLDT
CKKYFEEQSFHNRLNDTILKVLKQQQMKHKETHLTQAQLIEKLAQNQIDIETFKRLSTSSESEERYSNYSHKQITETIRH
IIKDKLTLETIAPLIDDITITQTKQLQEIYFKNSPLNIVEQSHLITSERNEVI
MVEAIGYVRQSTLKQQSLATQTSLIMETAKQYGWHNIEFYDDKKTGRNTKRSGYQKMVEMIISGECKVLCCYRLNRLHRN
LKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYR
QGHFVVHEEEAYTVKAVYRWYLQGLGYKKISQHLDNNPKLIPRKPYQVRNILLNPNYCGRVINKYGTFNDLVPSIVDIDT
FEEAQQCRVNKHHKQHISENKLKKLLRCPYCQATLTNLTIKKANHSLHYYVCPRNMNEAYHTCPFKGINALELESKVLDT
CKKYFEEQSFHNRLNDTILKVLKQQQMKHKETHLTQAQLIEKLAQNQIDIETFKRLSTSSESEERYSNYSHKQITETIRH
IIKDKLTLETIAPLIDDITITQTKQLQEIYFKNSPLNIVEQSHLITSERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=844894 QQ988_RS00170 WP_286096900.1 40350..41711(-) (ccrA) [Staphylococcus epidermidis strain NG02]
ATGGTCGAAGCCATTGGTTATGTACGTCAAAGTACACTCAAACAGCAAAGCTTAGCTACTCAAACGTCACTTATTATGGA
AACTGCAAAGCAATATGGTTGGCACAATATAGAATTTTATGACGATAAGAAAACTGGTCGAAATACAAAACGTTCAGGCT
ATCAAAAAATGGTAGAAATGATTATATCTGGAGAATGCAAAGTATTGTGTTGCTATCGCTTGAATCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTGAACATACTTATGAGTCTAGCGGAAATGGAGTCTAACAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCACCTTTTGGCTATCGTTATAGA
CAAGGTCATTTTGTTGTACATGAAGAAGAAGCCTATACAGTCAAAGCAGTATATCGCTGGTATTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTAGATAACAATCCTAAGCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAGTATGGAACATTTAATGATTTAGTCCCTTCTATTGTCGATATTGATACA
TTTGAAGAAGCACAGCAATGCCGTGTGAATAAACATCATAAACAACACATTTCTGAAAACAAATTAAAGAAGTTACTTAG
ATGTCCTTATTGTCAGGCAACGTTAACAAACTTAACGATTAAAAAAGCGAATCATTCTCTACATTACTACGTCTGTCCTA
GAAATATGAATGAAGCCTATCATACGTGTCCATTTAAAGGTATAAATGCACTAGAACTTGAAAGTAAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAGCAATCGTTTCATAATCGATTGAATGATACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGCACAATTGATTGAAAAGCTAGCTCAAAATCAAATTGATATCGAAACATTTA
AACGGTTATCTACTAGCTCTGAAAGTGAGGAGCGTTACTCTAATTATTCACATAAACAAATTACCGAAACAATCCGTCAT
ATAATCAAAGATAAATTGACGTTAGAAACCATAGCACCTTTAATTGATGACATTACGATAACTCAAACTAAACAATTACA
AGAGATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCTCATTTAATAACTTCTGAAAGGAATGAAGTCATAT
GA
ATGGTCGAAGCCATTGGTTATGTACGTCAAAGTACACTCAAACAGCAAAGCTTAGCTACTCAAACGTCACTTATTATGGA
AACTGCAAAGCAATATGGTTGGCACAATATAGAATTTTATGACGATAAGAAAACTGGTCGAAATACAAAACGTTCAGGCT
ATCAAAAAATGGTAGAAATGATTATATCTGGAGAATGCAAAGTATTGTGTTGCTATCGCTTGAATCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTGAACATACTTATGAGTCTAGCGGAAATGGAGTCTAACAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCACCTTTTGGCTATCGTTATAGA
CAAGGTCATTTTGTTGTACATGAAGAAGAAGCCTATACAGTCAAAGCAGTATATCGCTGGTATTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTAGATAACAATCCTAAGCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAGTATGGAACATTTAATGATTTAGTCCCTTCTATTGTCGATATTGATACA
TTTGAAGAAGCACAGCAATGCCGTGTGAATAAACATCATAAACAACACATTTCTGAAAACAAATTAAAGAAGTTACTTAG
ATGTCCTTATTGTCAGGCAACGTTAACAAACTTAACGATTAAAAAAGCGAATCATTCTCTACATTACTACGTCTGTCCTA
GAAATATGAATGAAGCCTATCATACGTGTCCATTTAAAGGTATAAATGCACTAGAACTTGAAAGTAAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAGCAATCGTTTCATAATCGATTGAATGATACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGCACAATTGATTGAAAAGCTAGCTCAAAATCAAATTGATATCGAAACATTTA
AACGGTTATCTACTAGCTCTGAAAGTGAGGAGCGTTACTCTAATTATTCACATAAACAAATTACCGAAACAATCCGTCAT
ATAATCAAAGATAAATTGACGTTAGAAACCATAGCACCTTTAATTGATGACATTACGATAACTCAAACTAAACAATTACA
AGAGATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCTCATTTAATAACTTCTGAAAGGAATGAAGTCATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.853 |
97.792 |
0.536 |
| ccrA | Staphylococcus aureus N315 |
52.37 |
97.792 |
0.512 |