Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NSY31_RS05745 Genome accession   NZ_CP127834
Coordinates   1115526..1116182 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain Ag109     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110526..1121182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NSY31_RS05720 (NSY31_05720) oppF 1111055..1111972 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NSY31_RS05725 (NSY31_05725) - 1112079..1113266 (+) 1188 WP_098081292.1 putative glycoside hydrolase -
  NSY31_RS05730 (NSY31_05730) - 1113384..1113962 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  NSY31_RS05735 (NSY31_05735) spx 1114141..1114536 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NSY31_RS05740 (NSY31_05740) - 1114594..1115250 (-) 657 WP_015417213.1 TerC family protein -
  NSY31_RS05745 (NSY31_05745) mecA 1115526..1116182 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NSY31_RS05750 (NSY31_05750) - 1116333..1117493 (+) 1161 WP_098081293.1 competence protein CoiA family protein -
  NSY31_RS05755 (NSY31_05755) pepF 1117721..1119550 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  NSY31_RS05760 (NSY31_05760) - 1119588..1119755 (-) 168 WP_003155026.1 hypothetical protein -
  NSY31_RS05765 (NSY31_05765) spxH 1120041..1120943 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=844513 NSY31_RS05745 WP_003155032.1 1115526..1116182(+) (mecA) [Bacillus velezensis strain Ag109]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=844513 NSY31_RS05745 WP_003155032.1 1115526..1116182(+) (mecA) [Bacillus velezensis strain Ag109]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTACATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895