Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   VZW04_RS15400 Genome accession   NZ_CP143092
Coordinates   3127638..3130487 (-) Length   949 a.a.
NCBI ID   WP_126851342.1    Uniprot ID   -
Organism   Escherichia coli strain EC190486     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3122638..3135487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VZW04_RS15365 (VZW04_15365) - 3122798..3123111 (+) 314 Protein_3010 Tn3 family transposase -
  VZW04_RS15370 (VZW04_15370) - 3123166..3123636 (-) 471 Protein_3011 M48 family metalloprotease -
  VZW04_RS15375 (VZW04_15375) psiE-GI 3123614..3124111 (-) 498 WP_000837725.1 heat resistance protein PsiE-GI -
  VZW04_RS15380 (VZW04_15380) kefB-GI 3124114..3125823 (-) 1710 WP_033554001.1 heat resistance system K+/H+ antiporter KefB-GI -
  VZW04_RS15385 (VZW04_15385) trx-GI 3125827..3126267 (-) 441 WP_000786815.1 heat resistance system thioredoxin Trx-GI -
  VZW04_RS15390 (VZW04_15390) - 3126257..3127402 (-) 1146 WP_004118192.1 hypothetical protein -
  VZW04_RS15395 (VZW04_15395) - 3127426..3127638 (-) 213 WP_000896642.1 hypothetical protein -
  VZW04_RS15400 (VZW04_15400) clpC 3127638..3130487 (-) 2850 WP_126851342.1 heat shock survival AAA family ATPase ClpK Regulator
  VZW04_RS15405 (VZW04_15405) hsp20 3130593..3131162 (-) 570 WP_000350436.1 small heat shock protein sHSP20 -
  VZW04_RS15410 (VZW04_15410) - 3131197..3131478 (-) 282 WP_000643630.1 helix-turn-helix domain-containing protein -
  VZW04_RS15415 (VZW04_15415) - 3131642..3131713 (+) 72 WP_369764383.1 IS1 family transposase -
  VZW04_RS15420 (VZW04_15420) - 3131788..3132485 (+) 698 WP_329490414.1 IS1-like element IS1A family transposase -
  VZW04_RS23560 - 3132691..3132817 (-) 127 Protein_3022 3'-5' exonuclease -
  VZW04_RS15430 (VZW04_15430) - 3132863..3133180 (-) 318 Protein_3023 resolvase -
  VZW04_RS15435 (VZW04_15435) - 3133175..3133921 (+) 747 Protein_3024 DUF4158 domain-containing protein -
  VZW04_RS15440 (VZW04_15440) - 3133955..3134923 (+) 969 WP_176555213.1 IS5 family transposase -
  VZW04_RS15445 (VZW04_15445) - 3135046..3135339 (-) 294 WP_000239862.1 biofilm development regulator YmgB/AriR family protein -

Sequence

Protein


Download         Length: 949 a.a.        Molecular weight: 104579.24 Da        Isoelectric Point: 5.5794

>NTDB_id=843246 VZW04_RS15400 WP_126851342.1 3127638..3130487(-) (clpC) [Escherichia coli strain EC190486]
MARKQCQVCGQPATVRVEANLNGRNSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGEDATPVAA
DTDDVVDASFGEPATAGSGAPRRRGSGLASRISEQSEALLQEAAKHAAEFGRSEVDTEHLLLALADSDVVKTILGQFKIK
VDDLKRQIESEARRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMARDGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQSELILFIDEVHTIVGAGQGGGEGGLD
VANVFKPMMARGELNLIGATTLNEYQKYIEKDAALERRFQPVTVPEPTVAQTIMILRGLRDTFEAHHKVSISEDAIIAAA
ELSDRYITARFPPDKAIDLLDQAAARVKLSATARPVAVQELESELHQLRREQDYVAARKQYDQAAELGKRIEAKEAELKK
LVEDWERERASGSAEVKAEHVAQVVSRLTGIPVNELTVEEREKLLHLEQRLHERLVGQDEAVRAVADAVRLSRAGLREGS
KPVATFLFLGPTGVGKTELAKALAESIYGDEHALLRIDMSEYGERHTVARLVGAPPGYVGYDEGGQLTEKVRRKPYSVLL
LDEIEKAHPDVYNILLQVFDDGRLTDGKGRMVNFTNTIIIATSNLGSDIIQRRLKAREAAGEEYEKTKAEVMDVLRGHFR
PEFLNRIDEIIVFHALGKEEIRHIVGLQLDRVARSAASQDVTLTFDQTLIDHFAEEGYKPEFGARELKRLIRSELETALA
REMLGGGIGKGDHASARWDDKAERVVFERKEPPQTPAEPEQPDVAKATETPHGDAGKDSSKKKSASDAS

Nucleotide


Download         Length: 2850 bp        

>NTDB_id=843246 VZW04_RS15400 WP_126851342.1 3127638..3130487(-) (clpC) [Escherichia coli strain EC190486]
ATGGCCAGAAAACAATGCCAGGTCTGCGGCCAACCCGCCACCGTGCGGGTGGAAGCCAATCTCAACGGTCGTAACAGCAC
CATGCTGTTGTGCGACGACCATTACCGGCAATTAGTGCGCCAGCAAAAGCGCACCGTTTCGCCGCTGGAAGCCTTGTTCG
GCTCGCGCAGCGGCCTGTTCGAGGACTTCCTTGGCAGTGACTTCTTCCGCATCGGCGAAGACGCGACGCCAGTTGCCGCC
GATACCGATGACGTGGTCGATGCCTCGTTTGGCGAGCCCGCCACCGCAGGTTCGGGTGCGCCGCGCCGTCGCGGCAGTGG
GTTGGCCAGCCGCATCAGCGAACAGTCGGAAGCCTTGCTGCAGGAGGCCGCCAAACACGCTGCCGAATTTGGCCGCTCCG
AGGTGGATACCGAACATCTGCTGCTGGCGCTGGCCGACAGCGACGTGGTCAAGACCATCCTGGGTCAGTTCAAGATCAAG
GTCGATGACCTCAAGCGGCAGATCGAGTCTGAGGCCAGGCGCGGGGACAAGCCCTTCGAGGGCGAGATCGGCGTGTCGCC
GCGCGTGAAGGATGCGCTCAGCCGCGCCTTCGTGGCCTCCAATGAACTCGGCCATTCTTATGTCGGTCCAGAGCATTTCC
TGATCGGTCTGGCCGAGGAAGGCGAAGGGCTGGCCGCCAACCTGCTGCGCCGCTACGGCCTGACGCCGCAGGCGCTGCGC
CAACAGGTCAGCAAGGTGGTCGGCAAGGGCGCCGAGGATGGCCGCGCTGAGACGCCGACCAACACGCCAGAACTCGACAA
GTACTCGCGCGACCTGACCAAGATGGCGCGCGACGGCAAGCTCGACCCGGTGATCGGCCGCGCGCAGGAGATCGAAACCA
CCATCGAGGTGCTGGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCGGGTGTGGGCAAGACCGCCATCGTC
GAAGGGCTGGCGCAGCGCATGGTGGCGGGTGAAGTGCCCGAGACCTTGCGCGACAAGCGCCTGGTGGAACTCAACATCAA
CGCCATGGTGGCCGGCGCCAAATATCGCGGCGAGTTCGAGGAGCGCGTGCAGAAGGTGCTGAAGGAGGTGACCGAGCACC
AGAGCGAGCTGATTTTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGTGGCGAAGGCGGGCTGGAC
GTGGCCAACGTGTTCAAACCGATGATGGCGCGCGGTGAACTCAACCTGATCGGCGCCACGACGCTGAACGAGTACCAGAA
ATACATCGAGAAGGATGCCGCACTGGAGCGGCGCTTCCAGCCGGTGACGGTGCCCGAGCCGACGGTGGCCCAGACCATCA
TGATTCTGCGCGGCCTGCGCGACACCTTCGAGGCGCACCACAAGGTCAGCATCTCCGAGGACGCGATCATCGCGGCGGCC
GAGTTGTCCGACCGCTACATCACGGCGCGCTTCCCGCCGGACAAGGCGATCGACCTGCTCGACCAGGCGGCCGCGCGCGT
GAAGCTGTCGGCCACGGCCCGGCCGGTGGCCGTGCAGGAGCTGGAGTCCGAACTGCACCAGCTACGGCGTGAACAGGATT
ACGTGGCCGCGCGCAAGCAGTACGACCAGGCCGCCGAGCTCGGCAAGCGCATCGAAGCCAAGGAGGCCGAGCTCAAGAAG
CTCGTCGAGGACTGGGAGCGGGAGCGGGCCTCCGGCAGTGCCGAGGTCAAGGCGGAACACGTGGCGCAGGTTGTCTCGCG
CCTGACCGGCATCCCGGTCAACGAGTTGACGGTGGAAGAGCGCGAAAAGCTGCTGCACTTGGAACAACGGCTGCACGAGC
GCCTGGTGGGACAAGACGAGGCGGTCCGTGCCGTGGCCGATGCCGTGCGGCTATCCCGCGCCGGCCTGCGCGAAGGCAGT
AAACCGGTGGCTACCTTCCTGTTTCTGGGCCCGACCGGGGTGGGCAAGACCGAGCTCGCCAAGGCATTGGCCGAATCGAT
CTACGGCGATGAGCACGCCCTGTTGCGCATCGACATGTCGGAATATGGCGAACGCCATACCGTGGCGCGGCTGGTGGGCG
CGCCTCCGGGCTATGTCGGTTACGACGAAGGCGGTCAGCTCACCGAGAAGGTGCGGCGCAAGCCCTACAGCGTGCTGCTG
CTCGACGAGATCGAGAAGGCACACCCTGACGTCTACAACATCCTGCTGCAAGTGTTTGACGACGGTCGCCTCACCGACGG
CAAGGGCCGGATGGTGAATTTCACCAACACCATCATCATCGCCACGTCCAACCTGGGTTCGGACATCATCCAGCGACGGC
TGAAGGCGCGTGAGGCGGCTGGCGAGGAGTACGAAAAGACCAAGGCCGAGGTCATGGACGTGCTGCGCGGCCACTTCCGG
CCCGAGTTCCTCAACCGCATCGACGAGATCATCGTCTTCCATGCGCTGGGCAAGGAGGAGATCCGCCACATCGTCGGCCT
GCAGCTCGATCGCGTGGCGCGCAGCGCCGCCAGCCAGGACGTGACGCTCACTTTCGATCAGACGCTGATCGACCATTTCG
CGGAAGAAGGCTACAAGCCCGAGTTCGGTGCGCGTGAACTCAAGCGCCTGATCCGCAGCGAGCTGGAAACTGCGCTGGCG
CGCGAGATGCTCGGTGGCGGCATCGGCAAGGGCGATCACGCCAGCGCACGCTGGGACGACAAGGCCGAACGCGTGGTGTT
CGAACGCAAAGAGCCACCGCAGACCCCGGCCGAGCCGGAGCAGCCGGATGTCGCGAAGGCGACCGAGACGCCGCACGGCG
ACGCTGGCAAAGACTCGAGCAAGAAGAAGTCGGCGAGCGACGCATCTTGA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(449-547)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(123-171)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(199-248)

ATPase family associated with various cellular activities (AAA) (AAA)

(307-428)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(816-894)

AAA domain (Cdc48 subfamily) (AAA_2)

(641-810)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

50.692

83.772

0.425
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.371

85.037

0.369
  clpC Streptococcus thermophilus LMD-9

41.667

87.25

0.364
  clpC Streptococcus thermophilus LMG 18311

41.576

86.934

0.361