Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   QQO15_RS00180 Genome accession   NZ_CP127094
Coordinates   42011..43360 (-) Length   449 a.a.
NCBI ID   WP_096536501.1    Uniprot ID   -
Organism   Staphylococcus pseudintermedius strain 19KM0990     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 40531..73831 42011..43360 within 0


Gene organization within MGE regions


Location: 40531..73831
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQO15_RS00180 (QQO15_00180) ccrA 42011..43360 (-) 1350 WP_096536501.1 recombinase family protein Machinery gene
  QQO15_RS00185 (QQO15_00185) - 43549..44178 (-) 630 Protein_34 hypothetical protein -
  QQO15_RS00190 (QQO15_00190) - 44187..44525 (+) 339 Protein_35 recombinase family protein -
  QQO15_RS00195 (QQO15_00195) - 44637..44996 (-) 360 WP_001631039.1 hypothetical protein -
  QQO15_RS00200 (QQO15_00200) - 45203..45529 (+) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  QQO15_RS00205 (QQO15_00205) - 45859..47784 (+) 1926 WP_053027547.1 heavy metal translocating P-type ATPase -
  QQO15_RS00210 (QQO15_00210) - 49036..49341 (+) 306 WP_000677988.1 hypothetical protein -
  QQO15_RS00215 (QQO15_00215) - 49540..50403 (+) 864 WP_000680580.1 hypothetical protein -
  QQO15_RS00220 (QQO15_00220) - 50511..51986 (+) 1476 WP_001138664.1 DUF6038 family protein -
  QQO15_RS00225 (QQO15_00225) - 52212..53312 (+) 1101 WP_000449985.1 DNA polymerase -
  QQO15_RS00230 (QQO15_00230) - 53305..53676 (+) 372 WP_001058156.1 hypothetical protein -
  QQO15_RS00235 (QQO15_00235) - 53673..55316 (+) 1644 WP_001015578.1 DUF5906 domain-containing protein -
  QQO15_RS00240 (QQO15_00240) - 55542..57218 (+) 1677 WP_000676596.1 recombinase family protein -
  QQO15_RS00245 (QQO15_00245) - 57324..57662 (+) 339 WP_000171559.1 SAUGI family uracil-DNA glycosylase inhibitor -
  QQO15_RS00250 (QQO15_00250) - 57758..58069 (+) 312 WP_001083109.1 DUF960 family protein -
  QQO15_RS00255 (QQO15_00255) - 58085..58591 (+) 507 WP_000447786.1 DUF1643 domain-containing protein -
  QQO15_RS00260 (QQO15_00260) - 58740..59414 (-) 675 WP_001106056.1 IS6-like element IS257 family transposase -
  QQO15_RS00265 (QQO15_00265) - 59498..59839 (+) 342 WP_001797647.1 hydroxymethylglutaryl-CoA synthase -
  QQO15_RS00270 (QQO15_00270) - 60756..61499 (+) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  QQO15_RS00275 (QQO15_00275) - 61596..62024 (+) 429 WP_000872606.1 MaoC family dehydratase -
  QQO15_RS00280 (QQO15_00280) mecA 62070..64079 (-) 2010 WP_096636819.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  QQO15_RS00285 (QQO15_00285) - 64176..64283 (+) 108 Protein_54 beta-lactam sensor/signal transducer MecR1 -
  QQO15_RS00290 (QQO15_00290) - 64324..64998 (+) 675 Protein_55 IS6 family transposase -
  QQO15_RS00295 (QQO15_00295) - 65058..65486 (-) 429 WP_000671996.1 VOC family protein -
  QQO15_RS00300 (QQO15_00300) - 65567..66496 (+) 930 WP_000750311.1 HTH domain-containing protein -
  QQO15_RS00305 (QQO15_00305) - 66658..68646 (+) 1989 WP_001038847.1 hypothetical protein -
  QQO15_RS00310 (QQO15_00310) - 68841..69950 (+) 1110 WP_000283873.1 DNA polymerase -
  QQO15_RS00315 (QQO15_00315) - 69943..70311 (+) 369 WP_001058155.1 hypothetical protein -
  QQO15_RS00320 (QQO15_00320) - 70311..71927 (+) 1617 WP_001015575.1 DUF5906 domain-containing protein -
  QQO15_RS00325 (QQO15_00325) - 72152..73831 (+) 1680 WP_000676592.1 recombinase family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52416.04 Da        Isoelectric Point: 9.9669

>NTDB_id=841613 QQO15_RS00180 WP_096536501.1 42011..43360(-) (ccrA) [Staphylococcus pseudintermedius strain 19KM0990]
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIRHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYHYH
NGTFTIDTVKAPTVKAVFNYYLQGYGYKKIAQYLEADDNFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVIRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPNHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIETKTTLNHEQLIEKLAQGKIDAETFREQTQSLHQQSKPISSISAYQIRKAFQ
NIIQQRFTLNMLYPYIDEINISKNKSLAGIYFKNEPLNIVNQTTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=841613 QQO15_RS00180 WP_096536501.1 42011..43360(-) (ccrA) [Staphylococcus pseudintermedius strain 19KM0990]
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCGACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAACAAATTACTGAACTGATTCAACAGGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGTCAAAAATACCATGTCCATATCTTAAGCGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCACTATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAACTTCATTAATCGTAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTATCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGCCATTCGACACTCACAAACATGACCGTCCGAAAACCAAATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAACCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCGAAAAGCTTTCCAA
AACATCATTCAACAACGTTTCACGCTAAACATGTTGTACCCCTATATTGATGAAATTAATATTTCTAAAAATAAAAGCCT
CGCTGGCATCTATTTCAAAAATGAACCTCTAAACATTGTCAATCAAACGACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Recombinase (Recombinase)

(170-250)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

94.209

100

0.942
  ccrA Staphylococcus aureus N315

74.833

100

0.748