Detailed information NTG0841399

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: VP459_RS08235
• Genome accession: NZ_CP142600
• Coordinates: 1748207..1750315 (-)
• Length: 702 a.a.
• NCBI ID: WP_001063342.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain M19060305
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1743207..1755315

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VP459_RS08220 (VP459_08225)	-	1745724..1745951 (+)	228	WP_000932073.1	FeoA family protein	-
VP459_RS08225 (VP459_08230)	feoB	1745963..1747957 (+)	1995	WP_000432895.1	ferrous iron transport protein B	-
VP459_RS08230 (VP459_08235)	-	1747970..1748140 (+)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
VP459_RS08235 (VP459_08240)	clpE	1748207..1750315 (-)	2109	WP_001063342.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
VP459_RS08240 (VP459_08245)	-	1750678..1751199 (+)	522	WP_000262592.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
VP459_RS08245 (VP459_08250)	-	1751370..1752536 (-)	1167	WP_000151986.1	hydroxymethylglutaryl-CoA synthase	-
VP459_RS08250 (VP459_08255)	-	1752790..1754067 (+)	1278	WP_001180327.1	hydroxymethylglutaryl-CoA reductase, degradative	-
VP459_RS08255 (VP459_08260)	-	1754206..1754637 (-)	432	WP_000455858.1	CHAP domain-containing protein	-
VP459_RS08260 (VP459_08265)	-	1755026..1755244 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78070.47 Da
• Isoelectric Point: 4.6408

>NTDB_id=841399 VP459_RS08235 WP_001063342.1 1748207..1750315(-) (clpE) [Staphylococcus aureus strain M19060305]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=841399 VP459_RS08235 WP_001063342.1 1748207..1750315(-) (clpE) [Staphylococcus aureus strain M19060305]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAGGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAGGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGCAATCTTACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAGACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGGGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACTGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCCGTTGCTACTGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCTCGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGTATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACTGACGTTAAACATGTGGATTTAGATATCGAGGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (264-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.212	91.595	0.442
clpE	Streptococcus pneumoniae Rx1	47.812	87.892	0.42
clpE	Streptococcus pneumoniae D39	47.812	87.892	0.42
clpE	Streptococcus pneumoniae R6	47.812	87.892	0.42
clpE	Streptococcus pneumoniae TIGR4	47.812	87.892	0.42
clpC	Lactococcus lactis subsp. cremoris KW2	46.044	90.028	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	43.951	93.02	0.409
clpC	Streptococcus thermophilus LMD-9	44.48	89.031	0.396
clpC	Streptococcus thermophilus LMG 18311	44.32	89.031	0.395
clpC	Streptococcus pneumoniae TIGR4	43.942	88.177	0.387
clpC	Streptococcus pneumoniae Rx1	43.942	88.177	0.387
clpC	Streptococcus pneumoniae D39	43.942	88.177	0.387
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.376	88.746	0.376