Detailed information NTG0841261

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QQO09_RS13445
• Genome accession: NZ_CP127017
• Coordinates: 2677659..2678546 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CC8-MSSA (PVL+) isolate Trinidad&Tobago_2020-042_7641M
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2672659..2683546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QQO09_RS13415 (QQO09_13420)	-	2672678..2672770 (+)	93	WP_010956583.1	hypothetical protein	-
QQO09_RS13420 (QQO09_13425)	-	2672878..2673375 (-)	498	WP_001065268.1	glutathione peroxidase	-
QQO09_RS13425 (QQO09_13430)	-	2673385..2673645 (-)	261	WP_001789910.1	hypothetical protein	-
QQO09_RS13430 (QQO09_13435)	-	2674027..2674140 (-)	114	WP_001791776.1	hypothetical protein	-
QQO09_RS13435 (QQO09_13440)	-	2674799..2676799 (-)	2001	WP_000776751.1	ABC transporter permease	-
QQO09_RS13440 (QQO09_13445)	-	2676796..2677551 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QQO09_RS13445 (QQO09_13450)	braS	2677659..2678546 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QQO09_RS13450 (QQO09_13455)	braR	2678557..2679222 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QQO09_RS13455 (QQO09_13460)	-	2679248..2679448 (-)	201	WP_000604728.1	hypothetical protein	-
QQO09_RS13460 (QQO09_13465)	-	2679646..2681070 (+)	1425	WP_000953744.1	alkaline phosphatase	-
QQO09_RS14090	-	2681130..2681231 (-)	102	WP_000731972.1	SE2200 family small protein	-
QQO09_RS13470 (QQO09_13475)	-	2681353..2681808 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QQO09_RS13475 (QQO09_13480)	-	2682053..2682814 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=841261 QQO09_RS13445 WP_000143419.1 2677659..2678546(-) (braS) [Staphylococcus aureus strain CC8-MSSA (PVL+) isolate Trinidad&Tobago_2020-042_7641M]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=841261 QQO09_RS13445 WP_000143419.1 2677659..2678546(-) (braS) [Staphylococcus aureus strain CC8-MSSA (PVL+) isolate Trinidad&Tobago_2020-042_7641M]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997