Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   VKP34_RS07570 Genome accession   NZ_CP142358
Coordinates   1488572..1491400 (-) Length   942 a.a.
NCBI ID   WP_136112144.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 6702-99     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1483572..1496400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP34_RS07540 (VKP34_07540) - 1484248..1485213 (+) 966 WP_002988504.1 LacI family DNA-binding transcriptional regulator -
  VKP34_RS07545 (VKP34_07545) nusB 1485354..1485806 (-) 453 WP_002983167.1 transcription antitermination factor NusB -
  VKP34_RS07550 (VKP34_07550) - 1485799..1486188 (-) 390 WP_002983163.1 Asp23/Gls24 family envelope stress response protein -
  VKP34_RS07555 (VKP34_07555) efp 1486234..1486791 (-) 558 WP_002988496.1 elongation factor P -
  VKP34_RS07560 (VKP34_07560) - 1486887..1487348 (-) 462 WP_002988493.1 deoxycytidylate deaminase -
  VKP34_RS07565 (VKP34_07565) - 1487383..1488456 (-) 1074 WP_136112135.1 M24 family metallopeptidase -
  VKP34_RS07570 (VKP34_07570) uvrA 1488572..1491400 (-) 2829 WP_136112144.1 excinuclease ABC subunit UvrA Machinery gene
  VKP34_RS07575 (VKP34_07575) - 1491603..1492547 (+) 945 WP_011888617.1 magnesium transporter CorA family protein -
  VKP34_RS07580 (VKP34_07580) - 1492680..1493335 (+) 656 Protein_1448 DUF1129 domain-containing protein -
  VKP34_RS07585 (VKP34_07585) rpsR 1493468..1493707 (-) 240 WP_002983142.1 30S ribosomal protein S18 -
  VKP34_RS07590 (VKP34_07590) ssb 1493872..1494363 (-) 492 WP_002983122.1 single-stranded DNA-binding protein Machinery gene
  VKP34_RS07595 (VKP34_07595) rpsF 1494385..1494675 (-) 291 WP_002983117.1 30S ribosomal protein S6 -
  VKP34_RS07600 (VKP34_07600) - 1494848..1495141 (-) 294 WP_136112136.1 hypothetical protein -

Sequence

Protein


Download         Length: 942 a.a.        Molecular weight: 104034.22 Da        Isoelectric Point: 6.0690

>NTDB_id=840918 VKP34_RS07570 WP_136112144.1 1488572..1491400(-) (uvrA) [Streptococcus pyogenes strain 6702-99]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINEHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKGKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide


Download         Length: 2829 bp        

>NTDB_id=840918 VKP34_RS07570 WP_136112144.1 1488572..1491400(-) (uvrA) [Streptococcus pyogenes strain 6702-99]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTCGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGAGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAACAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGCGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAAAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGGGATTTAGTTCT
TTATGGTTCAGGGGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGTGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCGACACAGATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGCCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGTCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTACAAAGGAAAAAATATCGCAGAAGTCCTTGATATGACTGTGGATGATGCCTTGGTATTTTTC
TCTGCTATTCCTAAAATCGCTCGAAAAATTCAAACGATTAAGGATGTTGGACTTGGTTATGTGACCTTAGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTGGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGCAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCTACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

84.607

100

0.846
  uvrA Streptococcus pneumoniae TIGR4

84.607

100

0.846
  uvrA Streptococcus pneumoniae D39

84.607

100

0.846