Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   VKP36_RS08545 Genome accession   NZ_CP142357
Coordinates   1722217..1722984 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain AW-534     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1717217..1727984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS08530 (VKP36_08530) hexB 1717736..1719718 (-) 1983 WP_010922757.1 DNA mismatch repair endonuclease MutL Machinery gene
  VKP36_RS08535 (VKP36_08535) - 1719813..1720964 (-) 1152 WP_003058754.1 tyrosine-type recombinase/integrase -
  VKP36_RS08540 (VKP36_08540) - 1721213..1721356 (+) 144 WP_326624817.1 putative holin-like toxin -
  VKP36_RS08545 (VKP36_08545) irvR 1722217..1722984 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  VKP36_RS08550 (VKP36_08550) - 1723138..1723344 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  VKP36_RS08555 (VKP36_08555) - 1723378..1724145 (+) 768 WP_022555252.1 BRO family protein -
  VKP36_RS08560 (VKP36_08560) - 1724155..1724775 (+) 621 WP_326624821.1 Bro-N domain-containing protein -
  VKP36_RS08565 (VKP36_08565) - 1724805..1725047 (+) 243 WP_326624824.1 phage antirepressor protein -
  VKP36_RS08570 (VKP36_08570) - 1725304..1725636 (+) 333 WP_111681407.1 hypothetical protein -
  VKP36_RS08575 (VKP36_08575) - 1725633..1725773 (+) 141 WP_014612652.1 hypothetical protein -
  VKP36_RS08580 (VKP36_08580) - 1725754..1725951 (+) 198 WP_022555260.1 hypothetical protein -
  VKP36_RS08585 (VKP36_08585) - 1725964..1726326 (+) 363 WP_000206026.1 hypothetical protein -
  VKP36_RS08590 (VKP36_08590) - 1726323..1726652 (+) 330 WP_326624831.1 hypothetical protein -
  VKP36_RS08595 (VKP36_08595) - 1726655..1726927 (+) 273 WP_014407941.1 hypothetical protein -
  VKP36_RS08600 (VKP36_08600) - 1726928..1727785 (+) 858 WP_326624833.1 primase alpha helix C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=840834 VKP36_RS08545 WP_003058809.1 1722217..1722984(-) (irvR) [Streptococcus pyogenes strain AW-534]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=840834 VKP36_RS08545 WP_003058809.1 1722217..1722984(-) (irvR) [Streptococcus pyogenes strain AW-534]
GTGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4