Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   VKP36_RS07330 Genome accession   NZ_CP142357
Coordinates   1458584..1461412 (-) Length   942 a.a.
NCBI ID   WP_326625554.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain AW-534     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1453584..1466412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS07300 (VKP36_07300) - 1454262..1455227 (+) 966 WP_002988504.1 LacI family DNA-binding transcriptional regulator -
  VKP36_RS07305 (VKP36_07305) nusB 1455368..1455820 (-) 453 WP_326624628.1 transcription antitermination factor NusB -
  VKP36_RS07310 (VKP36_07310) - 1455813..1456202 (-) 390 WP_002983163.1 Asp23/Gls24 family envelope stress response protein -
  VKP36_RS07315 (VKP36_07315) efp 1456248..1456805 (-) 558 WP_002993230.1 elongation factor P -
  VKP36_RS07320 (VKP36_07320) - 1456893..1457360 (-) 468 WP_021775474.1 deoxycytidylate deaminase -
  VKP36_RS07325 (VKP36_07325) - 1457395..1458468 (-) 1074 WP_136118222.1 M24 family metallopeptidase -
  VKP36_RS07330 (VKP36_07330) uvrA 1458584..1461412 (-) 2829 WP_326625554.1 excinuclease ABC subunit UvrA Machinery gene
  VKP36_RS07335 (VKP36_07335) - 1461615..1462559 (+) 945 WP_011888617.1 magnesium transporter CorA family protein -
  VKP36_RS07340 (VKP36_07340) - 1462691..1463347 (+) 657 WP_002983144.1 DUF1129 domain-containing protein -
  VKP36_RS07345 (VKP36_07345) rpsR 1463478..1463717 (-) 240 WP_002983142.1 30S ribosomal protein S18 -
  VKP36_RS07350 (VKP36_07350) ssbA 1463882..1464373 (-) 492 WP_002993238.1 single-stranded DNA-binding protein Machinery gene
  VKP36_RS07355 (VKP36_07355) rpsF 1464395..1464685 (-) 291 WP_002983117.1 30S ribosomal protein S6 -
  VKP36_RS07360 (VKP36_07360) - 1464858..1465151 (-) 294 WP_002983113.1 hypothetical protein -

Sequence

Protein


Download         Length: 942 a.a.        Molecular weight: 104064.21 Da        Isoelectric Point: 6.0690

>NTDB_id=840820 VKP36_RS07330 WP_326625554.1 1458584..1461412(-) (uvrA) [Streptococcus pyogenes strain AW-534]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
GQHKTVFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITSQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide


Download         Length: 2829 bp        

>NTDB_id=840820 VKP36_RS07330 WP_326625554.1 1458584..1461412(-) (uvrA) [Streptococcus pyogenes strain AW-534]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATCAATGGGCATGGTGCTATCACGGCGTCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCTCCTGTTGTTCGTCGGAAGAAG
GGGCAACACAAAACAGTTTTTGAGAAAATTCAAAAAGACGGCTATGTCCGTGTGCGCGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCAGAGTTGTCCAAAAGTAAGATGCACAACATTGAGGTGGTTATTGACCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGATTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTAACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCTTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAATTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATCCATGACCGTCTGACATTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTGTCACGGGCTGCTGGGACTTTATCAGGTGGTGAAAGTCAACGAATCAGGTTAGCAACACAAATTGGTTCTAACCT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCATCAAAGAGACAATGACCGTTTGATCGAGAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGAGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGCCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGTTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCGGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGCAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

85.032

100

0.85
  uvrA Streptococcus pneumoniae TIGR4

85.032

100

0.85
  uvrA Streptococcus pneumoniae D39

85.032

100

0.85