Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   VKP36_RS03765 Genome accession   NZ_CP142357
Coordinates   748080..748556 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain AW-534     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 743080..753556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS03740 (VKP36_03740) - 743121..743909 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  VKP36_RS03745 (VKP36_03745) - 743949..745055 (+) 1107 WP_014407520.1 NAD(P)/FAD-dependent oxidoreductase -
  VKP36_RS03750 (VKP36_03750) rfbA 745113..745982 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  VKP36_RS03755 (VKP36_03755) - 745982..746575 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  VKP36_RS03760 (VKP36_03760) rfbB 746819..747859 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  VKP36_RS03765 (VKP36_03765) mutX 748080..748556 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  VKP36_RS03770 (VKP36_03770) - 748614..749795 (+) 1182 WP_136094382.1 AI-2E family transporter -
  VKP36_RS03775 (VKP36_03775) - 749785..751032 (+) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  VKP36_RS03780 (VKP36_03780) fbp54 751091..752743 (-) 1653 WP_111676419.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=840787 VKP36_RS03765 WP_002984880.1 748080..748556(+) (mutX) [Streptococcus pyogenes strain AW-534]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=840787 VKP36_RS03765 WP_002984880.1 748080..748556(+) (mutX) [Streptococcus pyogenes strain AW-534]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAAGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703