Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   VKP36_RS02415 Genome accession   NZ_CP142357
Coordinates   455258..455956 (-) Length   232 a.a.
NCBI ID   WP_085613747.1    Uniprot ID   O31050
Organism   Streptococcus pyogenes strain AW-534     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 450258..460956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS02390 (VKP36_02390) - 450421..450873 (+) 453 WP_227874870.1 ATP phosphoribosyltransferase regulatory subunit -
  VKP36_RS02395 (VKP36_02395) - 450824..451630 (+) 807 WP_326625187.1 portal protein -
  VKP36_RS02400 (VKP36_02400) - 452003..453128 (-) 1126 Protein_425 IS3 family transposase -
  VKP36_RS02405 (VKP36_02405) - 453148..453663 (+) 516 WP_322972656.1 helical hairpin domain-containing protein -
  VKP36_RS02410 (VKP36_02410) - 453879..455240 (-) 1362 WP_109821250.1 sensor histidine kinase -
  VKP36_RS02415 (VKP36_02415) scnR 455258..455956 (-) 699 WP_085613747.1 response regulator transcription factor Regulator
  VKP36_RS02420 (VKP36_02420) - 456154..456309 (+) 156 WP_023612114.1 lacticin 481 family lantibiotic -
  VKP36_RS02425 (VKP36_02425) - 456340..456495 (+) 156 WP_085613746.1 lacticin 481 family lantibiotic -
  VKP36_RS02430 (VKP36_02430) - 456694..456849 (+) 156 WP_136021211.1 lacticin 481 family lantibiotic -
  VKP36_RS02435 (VKP36_02435) - 456870..459653 (+) 2784 WP_326625203.1 type 2 lanthipeptide synthetase LanM family protein -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 26246.39 Da        Isoelectric Point: 6.1274

>NTDB_id=840778 VKP36_RS02415 WP_085613747.1 455258..455956(-) (scnR) [Streptococcus pyogenes strain AW-534]
MNFESQLLNKRILIVDDDVALSKSIKEVLISRDFKNISCAYSISEGIDIFSVSKIDLIILDVMLPDGEGHLLAKYIRKYS
DVPILFLTAKNNPDDEIRGLESGGDDYVTKPFLPKSLTYRIIALLRRAYKDESELIELTNCTIDLNNASVEKNGQHLSLT
PTEIQILRKLFSNKNYIASTESICDTVWGLESLGYEKSLMVHIRNIREKIEITPSKPNHLITVKGLGYKLVI

Nucleotide


Download         Length: 699 bp        

>NTDB_id=840778 VKP36_RS02415 WP_085613747.1 455258..455956(-) (scnR) [Streptococcus pyogenes strain AW-534]
ATGAATTTTGAGTCTCAATTATTGAATAAACGCATATTGATTGTCGACGATGATGTCGCACTTAGCAAATCAATTAAAGA
GGTACTTATCAGTCGGGATTTCAAGAATATCAGCTGTGCTTATAGTATAAGCGAAGGAATTGATATCTTCTCAGTTTCTA
AAATTGATCTCATTATTTTAGATGTTATGCTACCAGATGGAGAAGGGCACTTACTTGCAAAATACATTAGGAAATATTCA
GATGTGCCAATTCTCTTTTTAACAGCCAAAAACAATCCTGATGATGAAATTCGAGGACTTGAATCCGGAGGGGATGATTA
TGTTACGAAGCCATTTCTTCCCAAATCTTTAACATATCGTATTATTGCACTGTTGAGAAGGGCTTATAAAGATGAATCGG
AACTAATTGAGCTAACAAATTGTACCATAGACTTAAACAATGCAAGTGTTGAAAAAAATGGTCAACATTTGTCACTCACT
CCAACAGAAATACAAATCCTACGAAAATTATTTTCAAATAAAAATTATATTGCATCAACTGAATCGATTTGTGATACCGT
TTGGGGACTTGAGAGCCTTGGCTACGAAAAATCACTTATGGTACATATTCGTAATATCAGAGAAAAAATCGAGATAACTC
CATCTAAGCCAAATCATCTTATTACTGTAAAAGGGCTTGGTTATAAACTAGTTATATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-230)

Response regulator receiver domain (Response_reg)

(12-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O31050

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

40.948

100

0.409
  vicR Streptococcus mutans UA159

38.528

99.569

0.384
  micA Streptococcus pneumoniae Cp1015

37.826

99.138

0.375