Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   JG741_RS00435 Genome accession   NZ_AP024210
Coordinates   80866..82338 (+) Length   490 a.a.
NCBI ID   WP_021211938.1    Uniprot ID   -
Organism   Lactococcus cremoris strain G3-2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 75866..87338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JG741_RS13855 (LLG32_00840) - 76498..76938 (+) 441 WP_232034967.1 metallophosphoesterase -
  JG741_RS13860 (LLG32_00850) - 77030..77170 (+) 141 WP_232034968.1 hypothetical protein -
  JG741_RS00410 (LLG32_00860) - 77263..78174 (+) 912 WP_021212488.1 CHAP domain-containing protein -
  JG741_RS00415 - 78411..78773 (+) 363 Protein_80 TIGR02328 family protein -
  JG741_RS00420 (LLG32_00880) - 79097..79342 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  JG741_RS00425 (LLG32_00890) - 79475..80005 (+) 531 WP_011834860.1 YceD family protein -
  JG741_RS00430 (LLG32_00900) covR 80161..80853 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  JG741_RS00435 (LLG32_00910) covS 80866..82338 (+) 1473 WP_021211938.1 HAMP domain-containing histidine kinase Regulator
  JG741_RS00440 (LLG32_00920) - 82524..83765 (+) 1242 WP_015082643.1 ammonium transporter -
  JG741_RS00445 (LLG32_00930) - 83850..84191 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  JG741_RS00450 (LLG32_00940) murD 84360..85709 (+) 1350 WP_021211936.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  JG741_RS00455 (LLG32_00950) murG 85952..87025 (+) 1074 WP_061777813.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55891.76 Da        Isoelectric Point: 4.7018

>NTDB_id=84072 JG741_RS00435 WP_021211938.1 80866..82338(+) (covS) [Lactococcus cremoris strain G3-2]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=84072 JG741_RS00435 WP_021211938.1 80866..82338(+) (covS) [Lactococcus cremoris strain G3-2]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.694

100

0.947

Multiple sequence alignment