Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   VKP54_RS03835 Genome accession   NZ_CP142356
Coordinates   745737..746213 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain CT95-157     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 740737..751213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP54_RS03810 (VKP54_03810) - 740778..741566 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  VKP54_RS03815 (VKP54_03815) - 741606..742712 (+) 1107 WP_021733319.1 NAD(P)/FAD-dependent oxidoreductase -
  VKP54_RS03820 (VKP54_03820) rfbA 742770..743639 (+) 870 WP_111711407.1 glucose-1-phosphate thymidylyltransferase RfbA -
  VKP54_RS03825 (VKP54_03825) - 743639..744232 (+) 594 WP_031488331.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  VKP54_RS03830 (VKP54_03830) rfbB 744476..745516 (+) 1041 WP_010922196.1 dTDP-glucose 4,6-dehydratase -
  VKP54_RS03835 (VKP54_03835) mutX 745737..746213 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  VKP54_RS03840 (VKP54_03840) - 746271..747452 (+) 1182 WP_031488330.1 AI-2E family transporter -
  VKP54_RS03845 (VKP54_03845) - 747442..748689 (+) 1248 WP_111711406.1 tetratricopeptide repeat protein -
  VKP54_RS03850 (VKP54_03850) fbp54 748748..750400 (-) 1653 WP_111711405.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=840694 VKP54_RS03835 WP_002984880.1 745737..746213(+) (mutX) [Streptococcus pyogenes strain CT95-157]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=840694 VKP54_RS03835 WP_002984880.1 745737..746213(+) (mutX) [Streptococcus pyogenes strain CT95-157]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703