Detailed information NTG0840692

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VKP54_RS03605
• Genome accession: NZ_CP142356
• Coordinates: 701736..703835 (-)
• Length: 699 a.a.
• NCBI ID: WP_111711411.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain CT95-157
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 696736..708835

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP54_RS03580 (VKP54_03580)	-	697213..698052 (+)	840	WP_011017679.1	thymidylate synthase	-
VKP54_RS03585 (VKP54_03585)	-	698132..698629 (+)	498	WP_111711413.1	dihydrofolate reductase	-
VKP54_RS03590 (VKP54_03590)	clpX	698949..700178 (+)	1230	WP_031488352.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
VKP54_RS03595 (VKP54_03595)	yihA	700188..700787 (+)	600	WP_111711412.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
VKP54_RS03600 (VKP54_03600)	-	700935..701678 (+)	744	WP_002984942.1	hypothetical protein	-
VKP54_RS03605 (VKP54_03605)	clpC	701736..703835 (-)	2100	WP_111711411.1	AAA family ATPase	Regulator
VKP54_RS03610 (VKP54_03610)	rpiA	704214..704897 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-
VKP54_RS03615 (VKP54_03615)	-	704974..706185 (+)	1212	WP_002984934.1	phosphopentomutase	-
VKP54_RS03620 (VKP54_03620)	arsC	706204..706644 (+)	441	WP_063812328.1	arsenate reductase (glutaredoxin)	-
VKP54_RS03625 (VKP54_03625)	-	706628..707437 (+)	810	WP_002984930.1	purine-nucleoside phosphorylase	-
VKP54_RS03630 (VKP54_03630)	deoD	708100..708813 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77360.50 Da
• Isoelectric Point: 5.7823

>NTDB_id=840692 VKP54_RS03605 WP_111711411.1 701736..703835(-) (clpC) [Streptococcus pyogenes strain CT95-157]
MTHFSSKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIKQKDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=840692 VKP54_RS03605 WP_111711411.1 701736..703835(-) (clpC) [Streptococcus pyogenes strain CT95-157]
ATGACACATTTTTCTAGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAATCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTCACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGGGCAGGTTTTGATGATGGTAAACGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TTATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAAGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• AAA lid domain (AAA_lid_9) (259-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.884	100	0.474
clpE	Streptococcus mutans UA159	47.076	100	0.472
clpE	Streptococcus pneumoniae TIGR4	49.051	90.415	0.443
clpE	Streptococcus pneumoniae Rx1	49.051	90.415	0.443
clpE	Streptococcus pneumoniae D39	49.051	90.415	0.443
clpE	Streptococcus pneumoniae R6	49.051	90.415	0.443
clpC	Bacillus subtilis subsp. subtilis str. 168	44.962	95.136	0.428
clpC	Streptococcus pneumoniae Rx1	42.025	93.276	0.392
clpC	Streptococcus pneumoniae D39	42.025	93.276	0.392
clpC	Streptococcus thermophilus LMD-9	42.947	91.273	0.392
clpC	Streptococcus thermophilus LMG 18311	42.79	91.273	0.391
clpC	Streptococcus pneumoniae TIGR4	43.016	90.129	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus mutans UA159	41.875	91.559	0.383