Detailed information NTG0840649

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: VKP40_RS08660
• Genome accession: NZ_CP142355
• Coordinates: 1744334..1745101 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain A946
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1739334..1750101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP40_RS08645 (VKP40_08645)	hexB	1739865..1741847 (-)	1983	WP_326675770.1	DNA mismatch repair endonuclease MutL	Machinery gene
VKP40_RS08650 (VKP40_08650)	-	1741942..1743093 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
VKP40_RS08655 (VKP40_08655)	-	1743342..1743485 (+)	144	WP_011185066.1	putative holin-like toxin	-
VKP40_RS08660 (VKP40_08660)	irvR	1744334..1745101 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
VKP40_RS08665 (VKP40_08665)	-	1745255..1745461 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
VKP40_RS08670 (VKP40_08670)	-	1745495..1745683 (+)	189	Protein_1652	helix-turn-helix domain-containing protein	-
VKP40_RS08675 (VKP40_08675)	-	1745714..1746121 (+)	408	WP_002992501.1	hypothetical protein	-
VKP40_RS08680 (VKP40_08680)	-	1746134..1746256 (+)	123	WP_011285272.1	hypothetical protein	-
VKP40_RS08685 (VKP40_08685)	-	1746537..1747058 (+)	522	WP_247456465.1	Rha family transcriptional regulator	-
VKP40_RS08690 (VKP40_08690)	-	1747303..1747635 (+)	333	WP_002992497.1	hypothetical protein	-
VKP40_RS08695 (VKP40_08695)	-	1747635..1747826 (+)	192	WP_027968868.1	hypothetical protein	-
VKP40_RS08700 (VKP40_08700)	-	1747839..1748201 (+)	363	WP_000206026.1	hypothetical protein	-
VKP40_RS08705 (VKP40_08705)	-	1748198..1748527 (+)	330	WP_000174505.1	hypothetical protein	-
VKP40_RS08710 (VKP40_08710)	-	1748530..1748802 (+)	273	WP_000051914.1	hypothetical protein	-
VKP40_RS08715 (VKP40_08715)	-	1748803..1749660 (+)	858	WP_011185073.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=840649 VKP40_RS08660 WP_003058809.1 1744334..1745101(-) (irvR) [Streptococcus pyogenes strain A946]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=840649 VKP40_RS08660 WP_003058809.1 1744334..1745101(-) (irvR) [Streptococcus pyogenes strain A946]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4