Detailed information NTG0840525

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VKP53_RS05540
• Genome accession: NZ_CP142354
• Coordinates: 1102831..1104930 (+)
• Length: 699 a.a.
• NCBI ID: WP_136076637.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 6745-99
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1097831..1109930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP53_RS05515 (VKP53_05515)	deoD	1097854..1098567 (-)	714	WP_002984928.1	purine-nucleoside phosphorylase	-
VKP53_RS05520 (VKP53_05520)	-	1099230..1100039 (-)	810	WP_014635415.1	purine-nucleoside phosphorylase	-
VKP53_RS05525 (VKP53_05525)	arsC	1100023..1100463 (-)	441	WP_023605079.1	arsenate reductase (glutaredoxin)	-
VKP53_RS05530 (VKP53_05530)	-	1100482..1101693 (-)	1212	WP_023605078.1	phosphopentomutase	-
VKP53_RS05535 (VKP53_05535)	rpiA	1101770..1102453 (-)	684	WP_021733827.1	ribose-5-phosphate isomerase RpiA	-
VKP53_RS05540 (VKP53_05540)	clpC	1102831..1104930 (+)	2100	WP_136076637.1	AAA family ATPase	Regulator
VKP53_RS05545 (VKP53_05545)	-	1104988..1105731 (-)	744	WP_002984942.1	hypothetical protein	-
VKP53_RS05550 (VKP53_05550)	yihA	1105879..1106478 (-)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
VKP53_RS05555 (VKP53_05555)	clpX	1106488..1107717 (-)	1230	WP_111676489.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
VKP53_RS05560 (VKP53_05560)	-	1108037..1108534 (-)	498	WP_002984955.1	dihydrofolate reductase	-
VKP53_RS05565 (VKP53_05565)	-	1108614..1109453 (-)	840	WP_011017679.1	thymidylate synthase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77258.33 Da
• Isoelectric Point: 5.7790

>NTDB_id=840525 VKP53_RS05540 WP_136076637.1 1102831..1104930(+) (clpC) [Streptococcus pyogenes strain 6745-99]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVIRQKDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=840525 VKP53_RS05540 WP_136076637.1 1102831..1104930(+) (clpC) [Streptococcus pyogenes strain 6745-99]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCCACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGTACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGGGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGACGTCAAAAAACTTCAGGCAATTCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (259-353)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.942	100	0.472
clpE	Streptococcus mutans UA159	49.375	91.559	0.452
clpE	Streptococcus pneumoniae TIGR4	49.438	89.127	0.441
clpE	Streptococcus pneumoniae Rx1	49.438	89.127	0.441
clpE	Streptococcus pneumoniae D39	49.438	89.127	0.441
clpE	Streptococcus pneumoniae R6	49.438	89.127	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.662	95.136	0.425
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Streptococcus thermophilus LMG 18311	42.633	91.273	0.389
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Streptococcus mutans UA159	41.562	91.559	0.381