Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   VKP53_RS05315 Genome accession   NZ_CP142354
Coordinates   1060455..1060931 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain 6745-99     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1055455..1065931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS05300 (VKP53_05300) fbp54 1056268..1057920 (+) 1653 WP_032462947.1 Rqc2 family fibronectin-binding protein Fbp54 -
  VKP53_RS05305 (VKP53_05305) - 1057979..1059226 (-) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  VKP53_RS05310 (VKP53_05310) - 1059216..1060397 (-) 1182 WP_002990002.1 AI-2E family transporter -
  VKP53_RS05315 (VKP53_05315) mutX 1060455..1060931 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  VKP53_RS05320 (VKP53_05320) rfbB 1061152..1062192 (-) 1041 WP_326674689.1 dTDP-glucose 4,6-dehydratase -
  VKP53_RS05325 (VKP53_05325) - 1062436..1063029 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  VKP53_RS05330 (VKP53_05330) rfbA 1063029..1063898 (-) 870 WP_326674690.1 glucose-1-phosphate thymidylyltransferase RfbA -
  VKP53_RS05335 (VKP53_05335) - 1063956..1065062 (-) 1107 WP_326674691.1 FAD-binding oxidoreductase -
  VKP53_RS05340 (VKP53_05340) - 1065102..1065890 (-) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=840523 VKP53_RS05315 WP_002984880.1 1060455..1060931(-) (mutX) [Streptococcus pyogenes strain 6745-99]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=840523 VKP53_RS05315 WP_002984880.1 1060455..1060931(-) (mutX) [Streptococcus pyogenes strain 6745-99]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703