Detailed information NTG0840468

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: VKP53_RS00655
• Genome accession: NZ_CP142354
• Coordinates: 94269..95036 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 6745-99
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 89269..100036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP53_RS00630 (VKP53_00630)	-	89699..90418 (+)	720	WP_010921791.1	metal ABC transporter ATP-binding protein	-
VKP53_RS00635 (VKP53_00635)	-	90411..91226 (+)	816	WP_021340473.1	metal ABC transporter permease	-
VKP53_RS00640 (VKP53_00640)	-	91266..91649 (-)	384	WP_002987766.1	HIT family protein	-
VKP53_RS00645 (VKP53_00645)	-	91813..92958 (-)	1146	WP_326674820.1	site-specific integrase	-
VKP53_RS00650 (VKP53_00650)	-	93275..93418 (+)	144	WP_011185066.1	putative holin-like toxin	-
VKP53_RS00655 (VKP53_00655)	irvR	94269..95036 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
VKP53_RS00660 (VKP53_00660)	-	95190..95396 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
VKP53_RS00665 (VKP53_00665)	-	95430..95630 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
VKP53_RS00670 (VKP53_00670)	-	95651..96058 (+)	408	WP_011185070.1	hypothetical protein	-
VKP53_RS00675 (VKP53_00675)	-	96072..96701 (+)	630	WP_111688392.1	Rha family transcriptional regulator	-
VKP53_RS00680 (VKP53_00680)	-	96947..97288 (+)	342	WP_037588219.1	hypothetical protein	-
VKP53_RS00685 (VKP53_00685)	-	97275..97496 (+)	222	WP_003058793.1	hypothetical protein	-
VKP53_RS00690 (VKP53_00690)	-	97499..97690 (+)	192	WP_023080070.1	hypothetical protein	-
VKP53_RS00695 (VKP53_00695)	-	97702..98031 (+)	330	WP_000174505.1	hypothetical protein	-
VKP53_RS00700 (VKP53_00700)	-	98034..98306 (+)	273	WP_001100459.1	hypothetical protein	-
VKP53_RS00705 (VKP53_00705)	-	98307..99164 (+)	858	WP_032463081.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=840468 VKP53_RS00655 WP_003058809.1 94269..95036(-) (irvR) [Streptococcus pyogenes strain 6745-99]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=840468 VKP53_RS00655 WP_003058809.1 94269..95036(-) (irvR) [Streptococcus pyogenes strain 6745-99]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4