Detailed information NTG0840153

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: VKP56_RS07365
• Genome accession: NZ_CP142350
• Coordinates: 1463377..1466205 (-)
• Length: 942 a.a.
• NCBI ID: WP_038434249.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SS1445
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1458377..1471205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP56_RS07335 (VKP56_07335)	-	1459053..1460018 (+)	966	WP_002988504.1	LacI family DNA-binding transcriptional regulator	-
VKP56_RS07340 (VKP56_07340)	nusB	1460159..1460611 (-)	453	WP_326656866.1	transcription antitermination factor NusB	-
VKP56_RS07345 (VKP56_07345)	-	1460604..1460993 (-)	390	WP_002983163.1	Asp23/Gls24 family envelope stress response protein	-
VKP56_RS07350 (VKP56_07350)	efp	1461039..1461596 (-)	558	WP_002988496.1	elongation factor P	-
VKP56_RS07355 (VKP56_07355)	-	1461692..1462153 (-)	462	WP_002988493.1	deoxycytidylate deaminase	-
VKP56_RS07360 (VKP56_07360)	-	1462188..1463261 (-)	1074	WP_111713618.1	M24 family metallopeptidase	-
VKP56_RS07365 (VKP56_07365)	uvrA	1463377..1466205 (-)	2829	WP_038434249.1	excinuclease ABC subunit UvrA	Machinery gene
VKP56_RS07370 (VKP56_07370)	-	1466408..1467352 (+)	945	WP_002983147.1	magnesium transporter CorA family protein	-
VKP56_RS07375 (VKP56_07375)	-	1467484..1468140 (+)	657	WP_002983144.1	DUF1129 domain-containing protein	-
VKP56_RS07380 (VKP56_07380)	rpsR	1468273..1468512 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
VKP56_RS07385 (VKP56_07385)	ssb	1468677..1469168 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
VKP56_RS07390 (VKP56_07390)	rpsF	1469190..1469480 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
VKP56_RS07395 (VKP56_07395)	-	1469653..1469946 (-)	294	WP_002983113.1	hypothetical protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104044.18 Da
• Isoelectric Point: 6.1170

>NTDB_id=840153 VKP56_RS07365 WP_038434249.1 1463377..1466205(-) (uvrA) [Streptococcus pyogenes strain SS1445]
MQNKIIIHGAKAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
GQHKTVFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEITASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQHLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=840153 VKP56_RS07365 WP_038434249.1 1463377..1466205(-) (uvrA) [Streptococcus pyogenes strain SS1445]
ATGCAAAATAAAATAATAATTCATGGGGCAAAAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGACCAAAAAACCACCAGTAAGAACCCTCGCTCAACGGTTGGTACGGTTACGGAAATCAATGA
TTATTTACGTCTACTATATGCGCGTGTGGGCACACCTTACTGTATCAATGGGCATGGTGCTATCACGGCGTCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCTCCTGTTGTTCGTCGGAAGAAG
GGGCAACACAAAACAGTTTTTGAGAAAATTCAAAAAGACGGCTATGTCCGTGTGCGCGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCAGAGTTGTCCAAAAGTAAGATGCACAACATTGAGGTGGTTATTGACCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGATTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCTTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAATTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATCCATGACCGTCTGACATTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGTGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCAACACAAATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGACCGGGGGCAGGTGAGTTCGGTGGAGAAATTACTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAACAATCTTCAACACCTTGATGTTAGATTCCCTCTCGGCAAATTTATTGCTGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	85.032	100	0.85
uvrA	Streptococcus pneumoniae TIGR4	85.032	100	0.85
uvrA	Streptococcus pneumoniae D39	85.032	100	0.85