Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   VKP56_RS03690 Genome accession   NZ_CP142350
Coordinates   732531..733007 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain SS1445     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 727531..738007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP56_RS03665 (VKP56_03665) - 727569..728357 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  VKP56_RS03670 (VKP56_03670) - 728397..729506 (+) 1110 WP_136300774.1 NAD(P)/FAD-dependent oxidoreductase -
  VKP56_RS03675 (VKP56_03675) rfbA 729564..730433 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  VKP56_RS03680 (VKP56_03680) - 730433..731026 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  VKP56_RS03685 (VKP56_03685) rfbB 731270..732310 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  VKP56_RS03690 (VKP56_03690) mutX 732531..733007 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  VKP56_RS03695 (VKP56_03695) - 733065..734246 (+) 1182 WP_326657500.1 AI-2E family transporter -
  VKP56_RS03700 (VKP56_03700) - 734236..735483 (+) 1248 WP_111713233.1 tetratricopeptide repeat protein -
  VKP56_RS03705 (VKP56_03705) fbp54 735542..737194 (-) 1653 WP_136300772.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=840122 VKP56_RS03690 WP_002984880.1 732531..733007(+) (mutX) [Streptococcus pyogenes strain SS1445]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=840122 VKP56_RS03690 WP_002984880.1 732531..733007(+) (mutX) [Streptococcus pyogenes strain SS1445]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAAGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACTTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703