Detailed information NTG0840120

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VKP56_RS03460
• Genome accession: NZ_CP142350
• Coordinates: 687608..689707 (-)
• Length: 699 a.a.
• NCBI ID: WP_326657462.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SS1445
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 682608..694707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP56_RS03435 (VKP56_03435)	-	683085..683924 (+)	840	WP_011017679.1	thymidylate synthase	-
VKP56_RS03440 (VKP56_03440)	-	684004..684501 (+)	498	WP_002984955.1	dihydrofolate reductase	-
VKP56_RS03445 (VKP56_03445)	clpX	684821..686050 (+)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
VKP56_RS03450 (VKP56_03450)	yihA	686060..686659 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
VKP56_RS03455 (VKP56_03455)	-	686807..687550 (+)	744	WP_023613169.1	hypothetical protein	-
VKP56_RS03460 (VKP56_03460)	clpC	687608..689707 (-)	2100	WP_326657462.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VKP56_RS03465 (VKP56_03465)	rpiA	690085..690768 (+)	684	WP_115354168.1	ribose-5-phosphate isomerase RpiA	-
VKP56_RS03470 (VKP56_03470)	-	690845..692056 (+)	1212	WP_115354167.1	phosphopentomutase	-
VKP56_RS03475 (VKP56_03475)	arsC	692075..692515 (+)	441	WP_115354166.1	arsenate reductase (glutaredoxin)	-
VKP56_RS03480 (VKP56_03480)	-	692499..693308 (+)	810	WP_009880955.1	purine-nucleoside phosphorylase	-
VKP56_RS03485 (VKP56_03485)	deoD	693893..694606 (+)	714	WP_002990147.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77249.32 Da
• Isoelectric Point: 5.6779

>NTDB_id=840120 VKP56_RS03460 WP_326657462.1 687608..689707(-) (clpC) [Streptococcus pyogenes strain SS1445]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNQAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVIRQKDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=840120 VKP56_RS03460 WP_326657462.1 687608..689707(-) (clpC) [Streptococcus pyogenes strain SS1445]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGACATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAATATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGGGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCAAGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGACGTCAAAAAACTTCAGGCAATTCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (259-353)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.942	100	0.472
clpE	Streptococcus mutans UA159	49.375	91.559	0.452
clpE	Streptococcus pneumoniae TIGR4	49.438	89.127	0.441
clpE	Streptococcus pneumoniae Rx1	49.438	89.127	0.441
clpE	Streptococcus pneumoniae D39	49.438	89.127	0.441
clpE	Streptococcus pneumoniae R6	49.438	89.127	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.662	95.136	0.425
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Streptococcus thermophilus LMG 18311	42.633	91.273	0.389
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Streptococcus mutans UA159	41.562	91.559	0.381