Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   VKP35_RS04485 Genome accession   NZ_CP142349
Coordinates   870704..871180 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain 11RS100     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 865704..876180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS04460 (VKP35_04460) - 865745..866533 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  VKP35_RS04465 (VKP35_04465) - 866573..867679 (+) 1107 WP_326623381.1 FAD-dependent oxidoreductase -
  VKP35_RS04470 (VKP35_04470) rfbA 867737..868606 (+) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  VKP35_RS04475 (VKP35_04475) - 868606..869199 (+) 594 WP_002984882.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  VKP35_RS04480 (VKP35_04480) rfbB 869443..870483 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  VKP35_RS04485 (VKP35_04485) mutX 870704..871180 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  VKP35_RS04490 (VKP35_04490) - 871238..872419 (+) 1182 WP_326623385.1 AI-2E family transporter -
  VKP35_RS04495 (VKP35_04495) - 872409..873656 (+) 1248 WP_111713233.1 tetratricopeptide repeat protein -
  VKP35_RS04500 (VKP35_04500) fbp54 873715..875367 (-) 1653 WP_111713234.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=840039 VKP35_RS04485 WP_002984880.1 870704..871180(+) (mutX) [Streptococcus pyogenes strain 11RS100]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=840039 VKP35_RS04485 WP_002984880.1 870704..871180(+) (mutX) [Streptococcus pyogenes strain 11RS100]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAAGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACTTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703