Detailed information NTG0839992

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: VKP35_RS00640
• Genome accession: NZ_CP142349
• Coordinates: 95043..95819 (-)
• Length: 258 a.a.
• NCBI ID: WP_129304367.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 11RS100
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 90043..100819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP35_RS00615 (VKP35_00615)	-	90461..91180 (+)	720	WP_002986585.1	metal ABC transporter ATP-binding protein	-
VKP35_RS00620 (VKP35_00620)	-	91173..91988 (+)	816	WP_002986583.1	metal ABC transporter permease	-
VKP35_RS00625 (VKP35_00625)	-	92028..92411 (-)	384	WP_002986580.1	HIT family protein	-
VKP35_RS00630 (VKP35_00630)	-	92575..93720 (-)	1146	WP_151403091.1	tyrosine-type recombinase/integrase	-
VKP35_RS00635 (VKP35_00635)	-	94048..94191 (+)	144	WP_011185066.1	putative holin-like toxin	-
VKP35_RS00640 (VKP35_00640)	irvR	95043..95819 (-)	777	WP_129304367.1	helix-turn-helix transcriptional regulator	Regulator
VKP35_RS00645 (VKP35_00645)	-	95973..96179 (+)	207	WP_326622929.1	helix-turn-helix transcriptional regulator	-
VKP35_RS00650 (VKP35_00650)	-	96213..96413 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
VKP35_RS00655 (VKP35_00655)	-	96434..96841 (+)	408	WP_011185070.1	hypothetical protein	-
VKP35_RS00660 (VKP35_00660)	-	96855..97472 (+)	618	WP_023080068.1	Rha family transcriptional regulator	-
VKP35_RS00665 (VKP35_00665)	-	97706..98047 (+)	342	WP_023611295.1	hypothetical protein	-
VKP35_RS00670 (VKP35_00670)	-	98034..98255 (+)	222	WP_023611263.1	hypothetical protein	-
VKP35_RS00675 (VKP35_00675)	-	98258..98449 (+)	192	WP_010922764.1	hypothetical protein	-
VKP35_RS00680 (VKP35_00680)	-	98461..98790 (+)	330	WP_003058810.1	hypothetical protein	-
VKP35_RS00685 (VKP35_00685)	-	98793..99065 (+)	273	WP_001100459.1	hypothetical protein	-
VKP35_RS00690 (VKP35_00690)	-	99066..99923 (+)	858	WP_010922767.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 258 a.a.
• Molecular weight: 28976.37 Da
• Isoelectric Point: 4.4675

>NTDB_id=839992 VKP35_RS00640 WP_129304367.1 95043..95819(-) (irvR) [Streptococcus pyogenes strain 11RS100]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEDSKNTVVELFSYNYYDHAASAGTGQYLNDVQVET
IELPVDYDADFVIPVYGDSMEPKYHSGDYVFVKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDR
DSDFRIIGEVIGSFTSKS

Nucleotide

• Length: 777 bp

>NTDB_id=839992 VKP35_RS00640 WP_129304367.1 95043..95819(-) (irvR) [Streptococcus pyogenes strain 11RS100]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAATGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGATAGTAAGAATACAGTAGTAG
AATTATTCTCCTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACA
ATTGAATTACCAGTCGATTATGACGCTGATTTTGTCATACCGGTTTATGGCGATTCCATGGAACCTAAATACCATTCTGG
GGACTATGTATTTGTCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATA
TCAAACAACTTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGA
GATAGTGATTTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (144-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	35	100	0.407