Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   VR625_RS07195 Genome accession   NZ_CP142147
Coordinates   1549194..1552265 (-) Length   1023 a.a.
NCBI ID   WP_109166261.1    Uniprot ID   -
Organism   Streptomyces sp. DSS69     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1544194..1557265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VR625_RS07175 - 1545866..1546738 (-) 873 WP_345981872.1 hypothetical protein -
  VR625_RS07180 - 1546743..1547357 (-) 615 WP_109166264.1 papain-like cysteine protease family protein -
  VR625_RS07185 - 1547585..1548514 (+) 930 WP_109166263.1 hypothetical protein -
  VR625_RS07190 - 1548575..1549003 (-) 429 WP_345981873.1 Rieske (2Fe-2S) protein -
  VR625_RS07195 uvrA 1549194..1552265 (-) 3072 WP_109166261.1 excinuclease ABC subunit UvrA Machinery gene
  VR625_RS07200 - 1552444..1553133 (+) 690 WP_345981874.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  VR625_RS07205 - 1553211..1553867 (+) 657 WP_345981875.1 MBL fold metallo-hydrolase -
  VR625_RS07210 - 1554078..1555097 (-) 1020 WP_109166258.1 TerC family protein -

Sequence

Protein


Download         Length: 1023 a.a.        Molecular weight: 111890.28 Da        Isoelectric Point: 8.4409

>NTDB_id=839933 VR625_RS07195 WP_109166261.1 1549194..1552265(-) (uvrA) [Streptomyces sp. DSS69]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPIARQSPQAIVDKVLGLPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGTTIQLSEPPTLKKQEKHTIEVVIDRLTVKESAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCAYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEEKSLDEGAIHPWSHGHTK
EYFGRLIGALSKALGFRTDIPWAGLPQRAKKALLYGHKIQTEVRYRNRYGRERAYTTPAFEGAVQFVKRRHTEAESDSSR
ERFEGYMREVPCPTCEGTRLKPIVLAVTVMEKSIAEVSAMSISECAEFLGRLKLNARDKKIAERVLKEVNERLKFLVDVG
LDYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVA
DWVVDIGPGAGEHGGKVVHSGSLKELLANKESITGQYLSGKRSIPTPDARRPVDPARSLTVHGARENNLHDIDVSFPLGV
LTAVTGVSGSGKSTLVNDILYTHLARELNGAKSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRRLF
AETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEE
GLEFFEAVPTIARHLRTLNEVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLITVL
SGLVDKGNSVIVIEHNLDVIKTADWVIDMGPEGGNGGGLVVAEGTPEQVASVPASHTGKFLQGILDADRISEAAVPTGRG
TARRPAAKKTTAAARKKATATAATKKATATKATASKATASKAAAKKASATKTTAKKATRARKA

Nucleotide


Download         Length: 3072 bp        

>NTDB_id=839933 VR625_RS07195 WP_109166261.1 1549194..1552265(-) (uvrA) [Streptomyces sp. DSS69]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAACCTGAAGAACGTCTCGCTCGATCTCCCCCGTGACTCCCT
CATCGTCTTCACCGGGCTCTCCGGGTCGGGCAAGTCGTCCCTCGCGTTCGACACGATCTTCGCCGAGGGCCAGCGGCGCT
ACGTGGAGTCCCTCTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAGGGCCTC
TCGCCCGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCCACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTCCGGCTGCTCTTCGCCCGGATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGCCCCATCGCCCGCCAGTCGCCGC
AGGCCATCGTGGACAAGGTCCTCGGCCTGCCCGAGGGCAGCCGGTTCCAGGTGCTCTCGCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTCCAGACCAAGGGGTACAGCCGCGCGAGGGTCGACGGCACCACCATCCAGCT
CTCCGAGCCGCCCACGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCATCGACCGCCTCACCGTCAAGGAGAGCG
CCAAGCGCCGGCTCACCGACTCGGTGGAGACCGCCCTCGGCCTCTCCGGCGGCATGGTCGTCCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGGATGTATTCCGAGCACCTCTACTGCGCGTACGACGACCTCTCCTTCGAGGAGCT
GGAGCCGCGTTCGTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGACTGCACGGGTATCGGTACGCGCATGGAGGTCG
ACCCGGAGCTGATCGTGCCGGACGAGGAGAAGTCCCTCGACGAGGGTGCGATCCACCCCTGGTCCCACGGGCACACCAAG
GAGTATTTCGGCCGGCTGATCGGCGCGCTCTCCAAGGCGCTCGGCTTCCGCACCGACATCCCCTGGGCCGGACTGCCGCA
GCGCGCCAAGAAGGCCCTGCTGTACGGCCACAAGATCCAGACCGAGGTCCGCTACCGCAACCGGTACGGGCGCGAGCGCG
CCTACACCACCCCCGCCTTCGAAGGCGCGGTCCAGTTCGTCAAGCGGCGCCACACCGAGGCCGAGAGCGACTCCAGCCGG
GAGCGGTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGCGAGGGCACCCGGCTCAAGCCGATCGTCCTCGCGGT
GACGGTGATGGAGAAGTCCATCGCCGAGGTCTCCGCGATGTCGATCAGCGAGTGCGCCGAGTTCCTCGGCCGCCTGAAGC
TGAACGCCCGCGACAAGAAGATCGCCGAGCGGGTCCTCAAGGAGGTCAACGAGCGGCTGAAGTTCCTGGTCGACGTCGGC
CTGGACTACCTCTCGCTGAACCGCGCGGCCGGCACGCTCTCCGGCGGCGAGGCCCAGCGCATCCGGCTCGCCACCCAGAT
CGGCTCCGGCCTGGTCGGTGTGCTGTACGTCCTGGACGAGCCGTCCATCGGCCTGCACCAGCGCGACAACCACCGCCTGA
TCGAGACCCTGGTCCGGCTCCGCGACATGGGGAACACGCTCATCGTGGTGGAGCACGACGAGGACACGATCAAGGTGGCA
GACTGGGTCGTCGACATCGGCCCCGGCGCGGGTGAGCACGGTGGCAAGGTCGTCCACTCCGGCTCGCTCAAGGAGCTGCT
GGCCAACAAGGAGTCGATCACCGGCCAGTATCTGTCCGGCAAGCGGTCCATCCCGACACCGGATGCCCGCCGCCCGGTCG
ACCCGGCCCGCAGCCTCACGGTGCACGGCGCCCGGGAGAACAACCTCCACGACATCGACGTCTCCTTCCCGCTCGGCGTG
CTCACCGCCGTCACCGGCGTCTCCGGGTCGGGGAAGTCGACCCTGGTCAACGACATCCTCTACACCCACCTGGCCCGTGA
GCTGAACGGCGCCAAGTCGGTCCCCGGCCGCCACACCCGCGTCGACGGCGACGACCTCGTCGACAAGGTGGTCCACGTCG
ACCAGTCGCCGATCGGCCGGACCCCCCGGTCCAACCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAGGCTCTTC
GCCGAGACGATGGAGGCGAAGGTGCGCGGCTATCTGCCGGGCCGCTTCTCCTTCAACGTCAAGGGTGGCCGCTGCGAGAA
CTGCTCCGGCGACGGCACGATCAAGATCGAGATGAACTTCCTGCCCGATGTGTACGTCCCGTGCGAGGTCTGCCACGGTG
CGCGCTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAG
GGCCTGGAGTTCTTCGAGGCCGTCCCGACGATCGCCCGCCACCTCCGTACGCTCAACGAGGTGGGCCTCGGCTACGTCCG
GCTCGGGCAGTCCGCGCCGACCCTCTCCGGCGGTGAGGCGCAGCGCGTCAAGCTGGCGAGCGAGCTCCAGAAGCGCTCCA
CCGGCCGCACGGTGTACGTCCTGGACGAGCCGACCACCGGTCTCCACTTCGAGGACATCAGCAAGCTGATCACGGTCCTC
TCCGGCCTGGTCGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTGGACGTCATCAAGACCGCCGACTGGGTCAT
CGACATGGGCCCCGAAGGCGGCAACGGCGGCGGTCTGGTGGTCGCCGAGGGGACGCCCGAGCAGGTCGCCTCGGTCCCCG
CCAGCCACACCGGGAAGTTCCTCCAGGGGATCCTGGACGCGGACCGGATCAGCGAGGCCGCGGTGCCTACGGGCCGTGGG
ACGGCCCGTAGGCCGGCCGCGAAGAAGACCACGGCGGCCGCCAGGAAGAAGGCCACGGCGACGGCTGCCACCAAGAAGGC
GACCGCCACCAAGGCCACGGCGTCCAAGGCGACGGCGTCCAAGGCCGCGGCCAAGAAGGCGTCGGCCACGAAGACCACCG
CCAAGAAGGCGACGCGCGCCCGCAAGGCGTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

ABC transporter (ABC_tran)

(629-865)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.586

92.766

0.525
  uvrA Streptococcus pneumoniae TIGR4

56.586

92.766

0.525
  uvrA Streptococcus pneumoniae D39

56.586

92.766

0.525