Detailed information NTG0839890

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: VRA41_RS07640
• Genome accession: NZ_CP142105
• Coordinates: 1462121..1463197 (-)
• Length: 358 a.a.
• NCBI ID: WP_011226464.1
• Uniprot ID: Q5M2Z4
• Organism: Streptococcus thermophilus strain SCB0351
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1457121..1468197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VRA41_RS07620 (VRA41_07620)	-	1458233..1460299 (-)	2067	WP_011227498.1	cation:proton antiporter	-
VRA41_RS07625 (VRA41_07625)	-	1460308..1460550 (-)	243	WP_011227499.1	hypothetical protein	-
VRA41_RS07630 (VRA41_07630)	-	1460547..1461095 (-)	549	WP_004197152.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
VRA41_RS07635 (VRA41_07635)	-	1461092..1462036 (-)	945	WP_011226463.1	TIGR01212 family radical SAM protein	-
VRA41_RS07640 (VRA41_07640)	sepM	1462121..1463197 (-)	1077	WP_011226464.1	SepM family pheromone-processing serine protease	Regulator
VRA41_RS07645 (VRA41_07645)	coaD	1463175..1463672 (-)	498	WP_011226465.1	pantetheine-phosphate adenylyltransferase	-
VRA41_RS07650 (VRA41_07650)	rsmD	1463706..1464305 (-)	600	WP_011227500.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
VRA41_RS07655 (VRA41_07655)	trxB	1464396..1465349 (-)	954	WP_255136104.1	thioredoxin-disulfide reductase	-
VRA41_RS07660 (VRA41_07660)	-	1465382..1465606 (-)	225	WP_011226468.1	DUF4059 family protein	-
VRA41_RS07665 (VRA41_07665)	amiE	1465821..1466564 (-)	744	WP_011226469.1	amino acid ABC transporter ATP-binding protein	Regulator
VRA41_RS07670 (VRA41_07670)	-	1466564..1467310 (-)	747	WP_095559509.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39232.11 Da
• Isoelectric Point: 9.4944

>NTDB_id=839890 VRA41_RS07640 WP_011226464.1 1462121..1463197(-) (sepM) [Streptococcus thermophilus strain SCB0351]
MANKTKSKSLLEKMWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYTQFNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAVYQGLTLAGKEVSLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGAVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKADPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=839890 VRA41_RS07640 WP_011226464.1 1462121..1463197(-) (sepM) [Streptococcus thermophilus strain SCB0351]
GTGGCAAACAAGACAAAATCTAAATCGCTATTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATACTCAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGCATCAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCTACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGCAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGATCAAGAGTCCTGAGAATGTTAAGTTTAAACTGGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATGTTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGGCTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGGACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATGA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (137-206)

3D structure

• AlphaFold DB: Q5M2Z4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.757	95.251	0.598