Detailed information NTG0839877

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: VRA41_RS06645
• Genome accession: NZ_CP142105
• Coordinates: 1272262..1273347 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain SCB0351
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1267262..1278347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VRA41_RS06615 (VRA41_06615)	-	1267628..1268443 (-)	816	WP_011227405.1	Cof-type HAD-IIB family hydrolase	-
VRA41_RS06620 (VRA41_06620)	-	1268436..1269230 (-)	795	WP_011227406.1	HAD hydrolase family protein	-
VRA41_RS06625 (VRA41_06625)	-	1269413..1269790 (+)	378	WP_011226300.1	GntR family transcriptional regulator	-
VRA41_RS06630 (VRA41_06630)	-	1269795..1270493 (+)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
VRA41_RS06635 (VRA41_06635)	-	1270505..1271290 (+)	786	WP_002951425.1	hypothetical protein	-
VRA41_RS06640 (VRA41_06640)	-	1271340..1272269 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
VRA41_RS06645 (VRA41_06645)	amiE	1272262..1273347 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
VRA41_RS06650 (VRA41_06650)	amiD	1273357..1274283 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
VRA41_RS06655 (VRA41_06655)	amiC	1274283..1275776 (-)	1494	WP_011227407.1	ABC transporter permease	Regulator
VRA41_RS06660 (VRA41_06660)	amiA	1275838..1277805 (-)	1968	WP_011226784.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=839877 VRA41_RS06645 WP_011226304.1 1272262..1273347(-) (amiE) [Streptococcus thermophilus strain SCB0351]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=839877 VRA41_RS06645 WP_011226304.1 1272262..1273347(-) (amiE) [Streptococcus thermophilus strain SCB0351]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526