Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JN167_RS09720 Genome accession   NZ_AP024201
Coordinates   2028972..2029688 (+) Length   238 a.a.
NCBI ID   WP_000688486.1    Uniprot ID   A0A7U7PWL0
Organism   Staphylococcus argenteus strain Tokyo13069     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023972..2034688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JN167_RS09690 (TMSFP069_18640) - 2024527..2025153 (+) 627 WP_047437110.1 nitroreductase family protein -
  JN167_RS09695 (TMSFP069_18650) - 2025254..2026039 (+) 786 WP_047528398.1 carbon-nitrogen family hydrolase -
  JN167_RS13370 hld 2026559..2026639 (-) 81 WP_000046023.1 delta-hemolysin -
  JN167_RS09705 (TMSFP069_18670) - 2026929..2027492 (+) 564 WP_047437114.1 accessory gene regulator AgrB -
  JN167_RS09710 (TMSFP069_18680) agrD 2027496..2027636 (+) 141 WP_047437117.1 cyclic lactone autoinducer peptide AgrD -
  JN167_RS09715 agrC 2027661..2028953 (+) 1293 WP_047528400.1 quorum-sensing sensor histidine kinase AgrC -
  JN167_RS09720 (TMSFP069_18700) agrA 2028972..2029688 (+) 717 WP_000688486.1 quorum-sensing response regulator AgrA Regulator
  JN167_RS09725 (TMSFP069_18710) - 2030041..2031000 (-) 960 WP_047528401.1 carbohydrate kinase family protein -
  JN167_RS09730 (TMSFP069_18720) - 2030997..2032481 (-) 1485 WP_000141408.1 sucrose-6-phosphate hydrolase -
  JN167_RS09735 (TMSFP069_18730) - 2032630..2033580 (-) 951 WP_202257194.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27894.87 Da        Isoelectric Point: 5.8625

>NTDB_id=83986 JN167_RS09720 WP_000688486.1 2028972..2029688(+) (agrA) [Staphylococcus argenteus strain Tokyo13069]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDDPYEVLEQSKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=83986 JN167_RS09720 WP_000688486.1 2028972..2029688(+) (agrA) [Staphylococcus argenteus strain Tokyo13069]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAACCTATGGAAATTGCCCTCGCAACTGATGATCCTTATGAGGTGCTTGAGCAATCTAAAAATATGAATGATATAG
GTTGTTACTTTTTAGATATTCAACTTTCAACAGACATTAATGGTATTAAATTAGGTAGTGAAATACGTAAGCATGACCCT
GTTGGCAATATAATATTTGTTACTAGTCATAGTGAACTTACTTATTTAACATTTGTCTACAAAGTTGCAGCAATGGATTT
TATTTTTAAAGATGATCCTGCTGAATTAAAAACACGAATTATAGATTGTCTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATAGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATACGATGATATTATG
TTTTTCGAATCATCTACCAAATCGCATAGACTCATCGCCCATTTAGATAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAATTGAGTCAATTAGATGATCGTTTTTTCAGATGTCATAATAGTTTTGTTGTCAATCGTCATAATATCGAATCCATTG
ATTCGAAAGAACGAATTGTCTATTTTAAAAATAAAGAACATTGTTATGCATCGGTAAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PWL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

98.739

100

0.987

Multiple sequence alignment