Detailed information NTG0083984

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JN167_RS09075
• Genome accession: NZ_AP024201
• Coordinates: 1914228..1915271 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain Tokyo13069
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1909228..1920271

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN167_RS09045 (TMSFP069_17360)	-	1909639..1910886 (-)	1248	WP_000656301.1	aminopeptidase	-
JN167_RS09050 (TMSFP069_17370)	-	1910898..1911098 (-)	201	WP_000180459.1	DUF1128 family protein	-
JN167_RS09055 (TMSFP069_17380)	-	1911245..1911709 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
JN167_RS09060 (TMSFP069_17390)	-	1911716..1911991 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
JN167_RS09065 (TMSFP069_17400)	-	1912270..1913493 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
JN167_RS09070 (TMSFP069_17410)	vraR	1913609..1914238 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
JN167_RS09075 (TMSFP069_17420)	vraS	1914228..1915271 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JN167_RS09080 (TMSFP069_17430)	liaF	1915268..1915969 (-)	702	WP_047528366.1	cell wall-active antibiotics response protein LiaF	-
JN167_RS09085 (TMSFP069_17440)	-	1915984..1916370 (-)	387	WP_047528367.1	hypothetical protein	-
JN167_RS09090 (TMSFP069_17450)	map	1916624..1917382 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
JN167_RS09095 (TMSFP069_17460)	-	1917906..1918892 (+)	987	WP_047557232.1	FUSC family protein	-
JN167_RS09100 (TMSFP069_17470)	-	1919294..1919674 (-)	381	WP_225995313.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=83984 JN167_RS09075 WP_001017131.1 1914228..1915271(-) (vraS) [Staphylococcus argenteus strain Tokyo13069]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=83984 JN167_RS09075 WP_001017131.1 1914228..1915271(-) (vraS) [Staphylococcus argenteus strain Tokyo13069]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTTGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGACTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACAAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTCTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAGGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1