Detailed information NTG0839392

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLE01_RS12675
• Genome accession: NZ_CP126675
• Coordinates: 2307692..2308720 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis subsp. lactis strain E.0.1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2302692..2313720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLE01_RS12650 (LLE01_12620)	-	2302978..2303475 (-)	498	WP_021214977.1	nitroreductase family protein	-
LLE01_RS12655 (LLE01_12625)	-	2303462..2303671 (-)	210	WP_003132661.1	hypothetical protein	-
LLE01_RS12660 (LLE01_12630)	-	2303668..2304495 (-)	828	WP_010906344.1	radical SAM protein	-
LLE01_RS12665 (LLE01_12635)	-	2304488..2306611 (-)	2124	WP_010906345.1	radical SAM protein	-
LLE01_RS12670 (LLE01_12640)	-	2306714..2307571 (-)	858	WP_010906346.1	transcriptional regulator	-
LLE01_RS12675 (LLE01_12645)	sepM	2307692..2308720 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
LLE01_RS12680 (LLE01_12650)	coaD	2308707..2309204 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LLE01_RS12685 (LLE01_12655)	rsmD	2309252..2309791 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLE01_RS12690 (LLE01_12660)	-	2309962..2311182 (-)	1221	WP_003132654.1	MFS transporter	-
LLE01_RS12695 (LLE01_12665)	lmrP	2311266..2312492 (-)	1227	WP_021214981.1	multidrug efflux MFS transporter LmrP	-
LLE01_RS12700 (LLE01_12670)	-	2312680..2313174 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=839392 LLE01_RS12675 WP_010906347.1 2307692..2308720(-) (sepM) [Lactococcus lactis subsp. lactis strain E.0.1]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=839392 LLE01_RS12675 WP_010906347.1 2307692..2308720(-) (sepM) [Lactococcus lactis subsp. lactis strain E.0.1]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491