Detailed information NTG0839319

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QPR37_RS06960
• Genome accession: NZ_CP126631
• Coordinates: 1435455..1436498 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 33-40
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1430455..1441498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QPR37_RS06930 (QPR37_06930)	-	1431244..1431354 (+)	111	WP_001790257.1	hypothetical protein	-
QPR37_RS06935 (QPR37_06935)	-	1431383..1431796 (+)	414	WP_141060381.1	hypothetical protein	-
QPR37_RS06940 (QPR37_06940)	-	1431985..1432971 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
QPR37_RS06945 (QPR37_06945)	map	1433381..1434139 (+)	759	WP_063651082.1	type I methionyl aminopeptidase	-
QPR37_RS06950 (QPR37_06950)	-	1434356..1434742 (+)	387	WP_001110174.1	hypothetical protein	-
QPR37_RS06955 (QPR37_06955)	liaF	1434757..1435458 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QPR37_RS06960 (QPR37_06960)	vraS	1435455..1436498 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QPR37_RS06965 (QPR37_06965)	vraR	1436488..1437117 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QPR37_RS06970 (QPR37_06970)	-	1437230..1438447 (-)	1218	WP_063651080.1	YihY/virulence factor BrkB family protein	-
QPR37_RS06975 (QPR37_06975)	-	1438725..1439000 (-)	276	WP_063651078.1	YtxH domain-containing protein	-
QPR37_RS06980 (QPR37_06980)	-	1439007..1439471 (-)	465	WP_063651075.1	low molecular weight protein-tyrosine-phosphatase	-
QPR37_RS06985 (QPR37_06985)	-	1439618..1439818 (+)	201	WP_000180460.1	DUF1128 family protein	-
QPR37_RS06990 (QPR37_06990)	-	1439821..1441077 (+)	1257	WP_217151847.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=839319 QPR37_RS06960 WP_001017131.1 1435455..1436498(+) (vraS) [Staphylococcus aureus strain 33-40]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=839319 QPR37_RS06960 WP_001017131.1 1435455..1436498(+) (vraS) [Staphylococcus aureus strain 33-40]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1