Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QPL68_RS12730 Genome accession   NZ_CP126629
Coordinates   2623704..2624420 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 35-42     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2618704..2629420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QPL68_RS12710 (QPL68_12710) - 2619798..2620748 (+) 951 WP_259378428.1 LacI family DNA-binding transcriptional regulator -
  QPL68_RS12715 (QPL68_12715) - 2620897..2622381 (+) 1485 WP_063652457.1 sucrose-6-phosphate hydrolase -
  QPL68_RS12720 (QPL68_12720) - 2622378..2623337 (+) 960 WP_285146490.1 carbohydrate kinase -
  QPL68_RS12725 (QPL68_12725) - 2623525..2623632 (-) 108 WP_063652462.1 hypothetical protein -
  QPL68_RS12730 (QPL68_12730) agrA 2623704..2624420 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QPL68_RS12735 (QPL68_12735) agrC 2624439..2625722 (-) 1284 WP_259378429.1 quorum-sensing sensor histidine kinase AgrC -
  QPL68_RS12740 (QPL68_12740) agrD 2625752..2625895 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  QPL68_RS12745 (QPL68_12745) - 2625898..2626461 (-) 564 WP_001105699.1 accessory gene regulator ArgB-like protein -
  QPL68_RS12750 (QPL68_12750) hld 2626752..2626832 (+) 81 WP_000046022.1 delta-hemolysin -
  QPL68_RS12755 (QPL68_12755) - 2627431..2628216 (-) 786 WP_063652466.1 carbon-nitrogen family hydrolase -
  QPL68_RS12760 (QPL68_12760) - 2628593..2629219 (-) 627 WP_000522380.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=839304 QPL68_RS12730 WP_000688492.1 2623704..2624420(-) (agrA) [Staphylococcus aureus strain 35-42]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=839304 QPL68_RS12730 WP_000688492.1 2623704..2624420(-) (agrA) [Staphylococcus aureus strain 35-42]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1