Detailed information NTG0839064

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VFH86_RS10105
• Genome accession: NZ_CP142014
• Coordinates: 2258960..2261533 (-)
• Length: 857 a.a.
• NCBI ID: WP_001235058.1
• Uniprot ID: A0AAU8WIQ1
• Organism: Vibrio cholerae strain LK-18
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2253960..2266533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VFH86_RS10105 (VFH86_10105)	clpC	2258960..2261533 (-)	2574	WP_001235058.1	ATP-dependent chaperone ClpB	Regulator
VFH86_RS10110 (VFH86_10110)	pgeF	2261658..2262380 (-)	723	WP_142610684.1	peptidoglycan editing factor PgeF	-
VFH86_RS10115 (VFH86_10115)	rluD	2262383..2263357 (-)	975	WP_000941106.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
VFH86_RS10120 (VFH86_10120)	comL	2263512..2264237 (+)	726	WP_000877198.1	outer membrane protein assembly factor BamD	Machinery gene
VFH86_RS10125 (VFH86_10125)	raiA	2264639..2264965 (+)	327	WP_000700176.1	ribosome-associated translation inhibitor RaiA	-
VFH86_RS10130 (VFH86_10130)	pheA	2265205..2266380 (+)	1176	WP_142726725.1	prephenate dehydratase	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95791.72 Da
• Isoelectric Point: 5.3019

>NTDB_id=839064 VFH86_RS10105 WP_001235058.1 2258960..2261533(-) (clpC) [Vibrio cholerae strain LK-18]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLNVDVMQLRSKLGEMLDRLPKVSGIGGD
VQLSSALGSLFNLCDKVAQKRQDAYISSEIYLLAALEDKGPLGTLLKEFGLTEKKVSDAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLAILNEELQEKERDYAELEEVWKAEKAALSGTQHIKAALE
QARMDLEVARRAGDLNRMSELQYGRIPELEKQLDLAAQAEMQEMTLLRNKVTDAEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEEVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDSEDAMVRVDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFARLDYQGIKEQVMDVVSKHFRPEFLNRVDESVVFHPLGQEHIKSIASIQLARLRQRLAERDYQLEVDDEAL
DLIAHVGFDPVYGARPLKRAIQQNVENPLAKSILAGKFLPGSPILLSVKDGNIFASQ

Nucleotide

• Length: 2574 bp

>NTDB_id=839064 VFH86_RS10105 WP_001235058.1 2258960..2261533(-) (clpC) [Vibrio cholerae strain LK-18]
ATGCGTCTTGACAGATTTACGAGCAAATTTCAGATCGCGATTTCCGATGCCCAGTCATTAGCGCTCGGCCGTGATCATCA
ATATATCGAACCTGTGCACCTGATGGTGGCTCTGCTGGATCAAAACGGCAGCCCGATCCGCCCATTACTCACCATGCTTA
ATGTGGATGTGATGCAACTGCGCTCCAAACTTGGCGAAATGCTCGATCGTTTACCCAAAGTCAGTGGTATTGGTGGTGAT
GTACAGCTCTCTTCGGCGCTTGGCTCGCTGTTTAATCTGTGTGATAAGGTTGCGCAAAAGCGTCAAGATGCCTACATCTC
CTCTGAAATTTATCTCCTCGCCGCTTTGGAAGATAAAGGTCCACTTGGAACCTTGCTCAAAGAGTTCGGGCTGACCGAGA
AAAAAGTCTCTGATGCAATTGAAAAAATTCGTGGAGGCCAGAAGGTCAATGACCCGAATGCGGAAGAGCTGCGTCAAGCG
TTGGAAAAATTCACCATCGATCTCACTGAACGCGCTGAGCAGGGCAAACTCGATCCTGTGATCGGTCGTGATGATGAAAT
TCGCCGCACCATTCAAGTGCTGCAGCGTCGTACCAAAAACAACCCAGTGATCATCGGTGAACCCGGTGTGGGTAAAACTG
CGATTGTGGAAGGCTTGGCGCAGCGCATCATTAATAATGAAGTACCAGAAGGCCTGCGTGGACGCCGCGTATTGTCTTTA
GATATGGGCGCGCTGGTGGCTGGGGCGAAATACCGCGGCGAATTTGAAGAGCGCTTGAAATCAGTACTCAATGAGCTAGC
GAAAGAAGAAGGCAATATCATCCTCTTCATTGATGAGCTGCACACCATGGTTGGTGCGGGGAAAGGCGAAGGCTCGATGG
ATGCCGGCAACATGCTCAAACCCGCTTTGGCGCGTGGAGAATTGCACTGTGTCGGCGCAACCACTTTAGATGAGTACCGC
CAATACATCGAAAAAGATCCAGCGTTAGAGCGCCGCTTCCAAAAAGTGTTGGTGGATGAGCCCACGGTGGAAGATACCAT
CGCCATCTTGCGTGGATTGAAAGAGCGTTATGAACTGCATCACCATGTCGAAATCACAGATCCAGCGATTGTGGCGGCAG
CGAGCCTATCGCATCGCTATATTTCCGATCGCCAGTTGCCTGATAAAGCGATCGATTTGATCGATGAAGCGGCTTCAAGC
ATCCGGATGCAGATTGACTCCAAACCAGAAGCTCTGGATAAGCTTGAGCGCAAAATCATCCAACTGAAAATCGAGCAGCA
AGCGCTCTCTAATGAGCACGATGAAGCCAGTGAAAAACGCTTGGCGATCTTAAATGAAGAGCTGCAAGAGAAAGAGCGTG
ATTACGCGGAGTTGGAAGAAGTGTGGAAAGCTGAAAAGGCGGCACTCTCCGGCACGCAACATATTAAAGCGGCACTTGAA
CAAGCGCGGATGGATCTGGAAGTCGCTCGCCGTGCGGGGGATTTGAACCGCATGTCAGAGCTGCAATATGGTCGCATTCC
AGAGTTAGAAAAGCAGCTTGATCTGGCTGCGCAAGCCGAAATGCAGGAAATGACTCTGCTACGTAATAAAGTGACGGATG
CAGAAATTGCCGAAGTGCTTTCAAAACAGACTGGCATTCCAGTATCAAAAATGCTCGAAGCCGAGAAAGAAAAGTTGCTG
CGCATGGAAGAAGTGCTGCATAAACGCGTGATTGGCCAAAAAGAAGCGGTGGAAGTAGTCGCGAATGCGATCCGTCGTAG
CCGCGCGGGGCTTTCTGATCCGAATCGTCCGATTGGCTCCTTCTTATTCCTGGGGCCAACAGGGGTCGGTAAAACCGAGC
TGTGTAAAACCTTGGCTAACTTCCTGTTTGACAGTGAAGATGCCATGGTACGTGTGGATATGTCGGAATTTATGGAGAAA
CACTCGGTTGCTCGTTTAGTCGGTGCGCCTCCAGGTTATGTCGGCTATGAAGAAGGTGGCTACTTAACGGAAGCTGTACG
CCGTAAACCTTACTCGGTGATTTTGCTCGATGAAGTGGAAAAGGCGCACCCAGATGTCTTCAATATTCTGCTGCAAGTCT
TGGATGATGGTCGCTTGACGGACGGGCAAGGGCGCACGGTTGATTTTCGAAATACCGTGGTGATCATGACCTCCAACTTG
GGTTCAAGCCGTATCCAAGAAAATTTTGCAAGGTTGGATTATCAAGGTATCAAAGAACAAGTGATGGACGTAGTCAGCAA
ACACTTCCGTCCTGAGTTCTTGAACCGAGTGGATGAAAGTGTGGTATTCCATCCATTAGGACAAGAGCATATTAAGTCGA
TCGCTTCTATTCAGTTGGCCCGCCTACGTCAACGTTTGGCAGAGCGAGATTACCAACTAGAGGTTGATGATGAGGCGCTG
GATCTGATTGCTCATGTCGGCTTCGATCCGGTTTATGGTGCTCGTCCACTGAAACGCGCGATTCAACAAAATGTGGAAAA
CCCACTGGCCAAATCGATTCTGGCTGGTAAGTTCCTGCCTGGTTCACCTATTTTACTATCGGTAAAAGACGGGAATATTT
TCGCAAGCCAGTAG

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-335)

• AAA lid domain (AAA_lid_9) (342-442)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-843)

3D structure

• AlphaFold DB: A0AAU8WIQ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.454	100	0.478
clpC	Lactococcus lactis subsp. cremoris KW2	47.186	80.863	0.382