Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VJ737_RS10685 Genome accession   NZ_CP141909
Coordinates   2377321..2377998 (-) Length   225 a.a.
NCBI ID   WP_184589742.1    Uniprot ID   A0A7W4ZN37
Organism   Streptomyces sp. CGMCC 4.1772     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2372321..2382998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VJ737_RS10665 (VJ737_10665) - 2372718..2374388 (+) 1671 WP_184589734.1 sensor histidine kinase -
  VJ737_RS10670 (VJ737_10670) - 2374388..2375068 (+) 681 WP_184589736.1 response regulator -
  VJ737_RS10675 (VJ737_10675) - 2375102..2376694 (-) 1593 WP_184589738.1 cation acetate symporter -
  VJ737_RS10680 (VJ737_10680) - 2376691..2377251 (-) 561 WP_184589740.1 DUF485 domain-containing protein -
  VJ737_RS10685 (VJ737_10685) vraR 2377321..2377998 (-) 678 WP_184589742.1 response regulator transcription factor Regulator
  VJ737_RS10690 (VJ737_10690) - 2377995..2379146 (-) 1152 WP_184589744.1 histidine kinase -
  VJ737_RS10695 (VJ737_10695) - 2379143..2379667 (-) 525 WP_184589760.1 DUF1453 family protein -
  VJ737_RS10700 (VJ737_10700) - 2379967..2382090 (-) 2124 WP_184589762.1 DNA topoisomerase IV subunit B -
  VJ737_RS10705 (VJ737_10705) - 2382531..2382761 (+) 231 WP_184589764.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23991.54 Da        Isoelectric Point: 6.1278

>NTDB_id=838671 VJ737_RS10685 WP_184589742.1 2377321..2377998(-) (vraR) [Streptomyces sp. CGMCC 4.1772]
MTQEAERKPARVVVVDDQTVVREGIVMLLGLLPGIEVLGAAGDGEEAVRLVAELAPDVVLMDLRMPRCDGVEATRRIRAQ
HPGTQVVVLTTYADDESLFPALAAGARGYLTKDAGGDEIVRAVHSVLSGEAGLSPSIQRRLLERLAEPRPAAPAEAPDGL
TVRETEVLVLIADGLSNQEIGRRLHVSTATVKTHINNLFTKAGIKDRAQAVRYAYGKGLVRPPAG

Nucleotide


Download         Length: 678 bp        

>NTDB_id=838671 VJ737_RS10685 WP_184589742.1 2377321..2377998(-) (vraR) [Streptomyces sp. CGMCC 4.1772]
ATGACGCAGGAGGCCGAGCGGAAGCCCGCTCGGGTGGTGGTCGTGGACGACCAGACCGTGGTGCGGGAGGGCATCGTGAT
GCTGCTCGGTCTGCTCCCCGGAATCGAGGTGCTAGGCGCCGCCGGAGACGGTGAGGAGGCGGTGAGGCTCGTCGCCGAAC
TGGCCCCGGACGTGGTGCTGATGGACCTGCGCATGCCCCGCTGCGACGGAGTGGAGGCGACCCGCAGGATCCGCGCGCAG
CACCCCGGGACGCAGGTCGTGGTGCTCACGACGTACGCGGACGACGAGTCCCTGTTCCCGGCGCTGGCTGCCGGAGCGCG
CGGCTATCTCACGAAGGACGCGGGCGGAGACGAGATCGTGAGGGCCGTGCACAGTGTGCTGTCCGGGGAGGCGGGGCTCT
CGCCGAGCATCCAGAGGCGGCTGCTGGAGCGCCTGGCGGAGCCGAGACCGGCGGCGCCTGCGGAGGCGCCGGACGGGCTC
ACCGTGCGGGAGACGGAGGTGCTGGTCCTCATCGCCGACGGGCTCAGCAACCAGGAGATCGGCCGCAGACTCCATGTCTC
CACCGCGACCGTGAAGACCCATATCAACAACCTTTTCACCAAGGCGGGAATCAAGGACCGTGCCCAGGCGGTGCGTTACG
CCTATGGAAAGGGCCTGGTGCGGCCACCAGCGGGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-214)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7W4ZN37

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.336

93.778

0.369