Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VDS57_RS12670 Genome accession   NZ_CP141839
Coordinates   2392003..2392644 (+) Length   213 a.a.
NCBI ID   WP_014478974.1    Uniprot ID   -
Organism   Bacillus subtilis strain PN1236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2387003..2397644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VDS57_RS12640 (VDS57_12640) ydfE 2388197..2388820 (-) 624 WP_014478968.1 flavin reductase family protein -
  VDS57_RS12645 (VDS57_12645) ydfF 2388910..2389590 (+) 681 WP_324271373.1 winged helix-turn-helix domain-containing protein -
  VDS57_RS12650 (VDS57_12650) ydfG 2389671..2390114 (-) 444 WP_014478970.1 carboxymuconolactone decarboxylase family protein -
  VDS57_RS12655 (VDS57_12655) - 2390200..2390379 (-) 180 WP_010886421.1 hypothetical protein -
  VDS57_RS12660 (VDS57_12660) - 2390376..2390519 (-) 144 WP_014478971.1 hypothetical protein -
  VDS57_RS12665 (VDS57_12665) ydfH 2390787..2392010 (+) 1224 WP_033881070.1 two-component system sensor histidine kinase YdfH -
  VDS57_RS12670 (VDS57_12670) vraR 2392003..2392644 (+) 642 WP_014478974.1 two-component system response regulator YdfI Regulator
  VDS57_RS12675 (VDS57_12675) pleJ 2392760..2394934 (+) 2175 WP_069837277.1 MMPL family transporter -
  VDS57_RS12680 (VDS57_12680) - 2395068..2396420 (-) 1353 WP_014478984.1 IS1182 family transposase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 24004.93 Da        Isoelectric Point: 5.1938

>NTDB_id=838355 VDS57_RS12670 WP_014478974.1 2392003..2392644(+) (vraR) [Bacillus subtilis strain PN1236]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRSETQLTEKEVIVLKAI
AKGLKSKAIAFDLDVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=838355 VDS57_RS12670 WP_014478974.1 2392003..2392644(+) (vraR) [Bacillus subtilis strain PN1236]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAGTGAGACGCAGCTGACGGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGACGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-203)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.264

99.531

0.371