Detailed information NTG0083814

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SA834_RS13665
• Genome accession: NZ_AP024170
• Coordinates: 2736462..2737349 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain 834
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2731462..2742349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA834_RS13635	-	2731481..2731573 (+)	93	WP_010956583.1	hypothetical protein	-
SA834_RS13640 (SA834_25700)	-	2731681..2732178 (-)	498	WP_001065268.1	glutathione peroxidase	-
SA834_RS13645 (SA834_25710)	-	2732188..2732448 (-)	261	WP_001791974.1	hypothetical protein	-
SA834_RS13650	-	2732830..2732943 (-)	114	Protein_2663	hypothetical protein	-
SA834_RS13655 (SA834_25720)	-	2733602..2735602 (-)	2001	WP_000776751.1	ABC transporter permease	-
SA834_RS13660 (SA834_25730)	-	2735599..2736354 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SA834_RS13665 (SA834_25740)	braS	2736462..2737349 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SA834_RS13670 (SA834_25750)	braR	2737360..2738025 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SA834_RS13675 (SA834_25760)	-	2738051..2738251 (-)	201	WP_000604730.1	hypothetical protein	-
SA834_RS13680 (SA834_25770)	-	2738449..2739873 (+)	1425	WP_000953755.1	alkaline phosphatase	-
SA834_RS14565	-	2739933..2740034 (-)	102	WP_000731976.1	SE2200 family small protein	-
SA834_RS13690 (SA834_25780)	-	2740156..2740611 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SA834_RS13695 (SA834_25790)	-	2740856..2741617 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=83814 SA834_RS13665 WP_000143425.1 2736462..2737349(-) (braS) [Staphylococcus aureus strain 834]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=83814 SA834_RS13665 WP_000143425.1 2736462..2737349(-) (braS) [Staphylococcus aureus strain 834]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1