Detailed information NTG0083808

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SA834_RS09725
• Genome accession: NZ_AP024170
• Coordinates: 1986068..1987111 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 834
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1981068..1992111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA834_RS09695 (SA834_18230)	-	1981489..1982745 (-)	1257	WP_001795108.1	aminopeptidase	-
SA834_RS09700 (SA834_18240)	-	1982748..1982948 (-)	201	WP_000180460.1	DUF1128 family protein	-
SA834_RS09705 (SA834_18250)	-	1983095..1983559 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SA834_RS09710 (SA834_18260)	-	1983566..1983841 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SA834_RS09715 (SA834_18270)	-	1984119..1985336 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SA834_RS09720 (SA834_18280)	vraR	1985449..1986078 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SA834_RS09725 (SA834_18290)	vraS	1986068..1987111 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SA834_RS09730 (SA834_18300)	liaF	1987108..1987809 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SA834_RS09735 (SA834_18310)	-	1987824..1988210 (-)	387	WP_001110179.1	hypothetical protein	-
SA834_RS09740 (SA834_18320)	map	1988427..1989185 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SA834_RS09745 (SA834_18330)	-	1989716..1990702 (+)	987	WP_000999717.1	FUSC family protein	-
SA834_RS09750 (SA834_18340)	-	1991133..1991546 (-)	414	WP_001557448.1	hypothetical protein	-
SA834_RS09755	-	1991575..1991685 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=83808 SA834_RS09725 WP_001017131.1 1986068..1987111(-) (vraS) [Staphylococcus aureus strain 834]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=83808 SA834_RS09725 WP_001017131.1 1986068..1987111(-) (vraS) [Staphylococcus aureus strain 834]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1