Detailed information NTG0838056

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LL303_RS12470
• Genome accession: NZ_CP126467
• Coordinates: 2431959..2432987 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis subsp. lactis strain 303
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2426959..2437987

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL303_RS12440 (LL303_12410)	-	2427246..2427743 (-)	498	WP_021214977.1	nitroreductase family protein	-
LL303_RS12445 (LL303_12415)	-	2427730..2427939 (-)	210	WP_003132661.1	hypothetical protein	-
LL303_RS12450 (LL303_12420)	-	2427936..2428763 (-)	828	WP_010906344.1	radical SAM protein	-
LL303_RS12455 (LL303_12425)	-	2428756..2429955 (-)	1200	WP_249357283.1	hypothetical protein	-
LL303_RS12460 (LL303_12430)	-	2429952..2430878 (-)	927	WP_228777561.1	radical SAM protein	-
LL303_RS12465 (LL303_12435)	-	2430981..2431838 (-)	858	WP_031561135.1	transcriptional regulator	-
LL303_RS12470 (LL303_12440)	sepM	2431959..2432987 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
LL303_RS12475 (LL303_12445)	coaD	2432974..2433471 (-)	498	WP_031561141.1	pantetheine-phosphate adenylyltransferase	-
LL303_RS12480 (LL303_12450)	rsmD	2433519..2434058 (-)	540	WP_171031472.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LL303_RS12485 (LL303_12455)	-	2434229..2435449 (-)	1221	WP_003132654.1	MFS transporter	-
LL303_RS12490 (LL303_12460)	lmrP	2435532..2436758 (-)	1227	WP_031561146.1	multidrug efflux MFS transporter LmrP	-
LL303_RS12495 (LL303_12465)	-	2436946..2437440 (+)	495	WP_017865181.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=838056 LL303_RS12470 WP_010906347.1 2431959..2432987(-) (sepM) [Lactococcus lactis subsp. lactis strain 303]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=838056 LL303_RS12470 WP_010906347.1 2431959..2432987(-) (sepM) [Lactococcus lactis subsp. lactis strain 303]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491