Detailed information NTG0837453

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VLX10_RS14525
• Genome accession: NZ_CP141753
• Coordinates: 3150532..3153081 (-)
• Length: 849 a.a.
• NCBI ID: WP_003139311.1
• Uniprot ID: A0A0H2ZBC1
• Organism: Pseudomonas aeruginosa strain 2023CK-01336
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3145532..3158081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VLX10_RS14500 (VLX10_14500)	-	3145811..3146206 (+)	396	WP_003089513.1	DUF4280 domain-containing protein	-
VLX10_RS14505 (VLX10_14505)	-	3146229..3146765 (-)	537	WP_023095583.1	toxin-antitoxin system YwqK family antitoxin	-
VLX10_RS14510 (VLX10_14510)	tssI	3146776..3148782 (-)	2007	WP_023095584.1	type VI secretion system tip protein VgrG	-
VLX10_RS14515 (VLX10_14515)	-	3148819..3149886 (-)	1068	WP_023095585.1	M91 family zinc metallopeptidase	-
VLX10_RS14520 (VLX10_14520)	-	3149925..3150458 (-)	534	WP_003089506.1	hypothetical protein	-
VLX10_RS14525 (VLX10_14525)	clpC	3150532..3153081 (-)	2550	WP_003139311.1	type VI secretion system ATPase TssH	Regulator
VLX10_RS14530 (VLX10_14530)	tssG	3153083..3154099 (-)	1017	WP_003114517.1	type VI secretion system baseplate subunit TssG	-
VLX10_RS14535 (VLX10_14535)	tssF	3154063..3155856 (-)	1794	WP_019486282.1	type VI secretion system baseplate subunit TssF	-
VLX10_RS14540 (VLX10_14540)	tssE	3155840..3156265 (-)	426	WP_003089496.1	type VI secretion system baseplate subunit TssE	-
VLX10_RS14545 (VLX10_14545)	-	3156278..3156775 (-)	498	WP_003089495.1	Hcp family type VI secretion system effector	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 92457.70 Da
• Isoelectric Point: 5.1045

>NTDB_id=837453 VLX10_RS14525 WP_003139311.1 3150532..3153081(-) (clpC) [Pseudomonas aeruginosa strain 2023CK-01336]
MELAALIGRLNPDCRRALERAAQRCLQRTHHYVEIEHLLLELLDIDGGDFACLLPRFGLERDALVAEINLSLELFKAGNT
RTPALSAHTIGLLEDAVVHASVLGQAQIRSGLLLLALLDREERRALLLNSASSLLRIPHEALQANLLEWIQTSREQPPAP
NRPAAGGDKPESAPDPLLDQYTQDLTAEARAGRIDPIVGRDGEIRQCVDILLRRRQNNPILVGAPGVGKTAVVEGLALRI
AAGEVPPSLQEVILRVLDLGLLQAGASMKGEFEQRLKGVIDAVRNSAQPIILFIDEAHTLIGAGGAEGGSDAANLLKPAL
ARGELRTLAATTWLEYKKYFEKDPALTRRFQLVQVEEPDEATAVEMLRGVAGKLEQHHGVQIMDAAIVDAVKLSHRYISG
RQLPDKAISVLDTACARVALGQHDVPPPLESLRHREQALEEELQRLRREQATGLDHSARITALESESGDNRRTIRELETR
WDEEREAVRELLDTRRELLALSESADAAKPDEELDGRIDHLAAELARLAAGLEAIRQDDPLVPEQVDSRTVAAVIAGWTG
IPVGKMLADEAHAIRSLAQRMGQRVMGQEAALGAIAQRIQAYRAGLSDPAKPVGVFLLPGPTGVGKTETAYALADALYGG
ERNLISINLSEYQEAHTVSQLKGAPPGYVGYGSGGVLTEAVRRKPYSVVLLDEIEKAHPDVLEAFYNVFDKGVMEDGTGL
VVDFRNTVILATSNVGAELLLDSPAEQVATPAFDERLRKVLLQTFRPAFLARMTVVPYRPLEEATLEGIVVAKLEKLRER
YKAATGKQFDFDPAIVKAVLAKCSAAGARDIENVLMAQVTGKLAEWVLE

Nucleotide

• Length: 2550 bp

>NTDB_id=837453 VLX10_RS14525 WP_003139311.1 3150532..3153081(-) (clpC) [Pseudomonas aeruginosa strain 2023CK-01336]
ATGGAACTCGCCGCCCTGATCGGCCGCCTCAACCCGGACTGTCGCCGCGCCCTGGAGCGCGCCGCGCAACGCTGCCTGCA
ACGCACCCATCATTACGTAGAGATCGAGCACCTGCTGCTGGAGCTGCTGGACATCGACGGCGGCGACTTCGCCTGCCTGC
TGCCGCGCTTCGGCCTGGAGCGCGACGCCCTGGTCGCCGAGATCAACCTGTCGCTGGAGCTGTTCAAGGCCGGCAATACC
CGCACTCCGGCGCTGTCCGCGCACACCATCGGCCTGCTCGAGGACGCCGTGGTCCACGCCAGCGTGCTCGGCCAGGCGCA
GATCCGTTCCGGCCTGCTGCTGCTCGCCCTGCTCGACCGCGAGGAGCGCCGCGCCCTGCTGCTGAACAGCGCGTCGTCGC
TACTGCGGATTCCCCACGAGGCCTTGCAGGCCAACCTGCTGGAGTGGATCCAGACCTCCCGCGAACAGCCGCCCGCGCCG
AACCGCCCGGCTGCAGGCGGCGACAAGCCGGAAAGCGCCCCGGACCCGCTGCTCGACCAGTACACCCAGGACCTCACCGC
CGAGGCCCGCGCCGGGCGCATCGACCCCATAGTCGGGCGCGACGGGGAGATCCGCCAGTGCGTCGACATCCTCCTGCGCC
GGCGGCAGAACAACCCGATCCTGGTCGGCGCGCCGGGCGTCGGCAAGACCGCGGTGGTCGAGGGCCTGGCCCTACGCATC
GCCGCCGGCGAGGTGCCGCCGTCGTTGCAGGAGGTGATCCTGCGGGTGCTCGACCTCGGCCTGTTGCAGGCCGGCGCCAG
CATGAAGGGCGAGTTCGAGCAGCGCCTCAAGGGCGTGATCGACGCCGTGCGCAACAGCGCGCAGCCGATCATCCTGTTCA
TCGACGAGGCGCACACGCTGATCGGCGCCGGCGGCGCGGAAGGCGGCAGCGACGCCGCCAACCTGCTCAAGCCGGCCCTG
GCGCGCGGCGAGTTGCGCACCCTGGCGGCCACCACCTGGCTGGAATACAAGAAATACTTCGAGAAGGACCCGGCGCTGAC
CCGGCGCTTCCAGTTGGTCCAGGTCGAGGAGCCGGACGAGGCCACCGCCGTGGAGATGCTGCGCGGCGTCGCCGGCAAGC
TGGAACAGCATCACGGCGTGCAGATCATGGACGCGGCCATCGTCGATGCGGTGAAGCTGTCGCACCGCTACATCTCCGGC
CGCCAGTTACCGGACAAGGCGATCAGCGTGCTCGACACCGCCTGCGCGCGGGTCGCCCTCGGCCAGCACGACGTGCCGCC
GCCGCTGGAAAGCCTGCGCCACCGCGAGCAGGCGCTGGAAGAGGAATTGCAGCGGCTGCGCCGGGAACAGGCCACCGGCC
TCGACCACAGCGCGCGTATCACCGCCCTGGAAAGCGAGTCGGGCGATAACCGCCGGACCATCCGCGAGCTGGAGACCCGC
TGGGACGAGGAACGCGAAGCGGTGCGCGAACTGCTCGACACCCGCCGCGAATTGCTGGCCCTCAGCGAAAGCGCCGACGC
GGCCAAGCCCGACGAGGAACTGGACGGTCGCATCGACCACCTGGCCGCCGAACTGGCGCGCCTGGCGGCCGGCCTCGAAG
CCATCCGCCAGGACGACCCGCTGGTTCCCGAGCAGGTGGACTCGCGTACCGTGGCCGCGGTGATCGCCGGCTGGACCGGC
ATCCCGGTGGGCAAGATGCTCGCCGACGAAGCCCACGCCATCCGTTCCCTGGCGCAACGAATGGGCCAGCGGGTGATGGG
CCAGGAGGCCGCCCTGGGCGCCATCGCCCAGCGCATCCAGGCCTATCGCGCCGGACTCAGCGACCCGGCCAAGCCGGTCG
GCGTATTCCTCCTGCCCGGCCCCACCGGCGTGGGCAAGACCGAGACCGCCTACGCCCTGGCCGACGCCCTCTACGGCGGC
GAACGCAACCTGATCAGCATCAACCTCTCCGAGTACCAGGAGGCCCACACCGTCAGCCAGCTCAAGGGCGCCCCGCCCGG
CTACGTCGGCTACGGCAGCGGCGGCGTGCTCACCGAAGCGGTGCGCCGCAAGCCCTATTCGGTGGTGCTGCTGGACGAGA
TCGAGAAAGCCCATCCGGACGTGCTGGAAGCCTTCTACAACGTGTTCGACAAGGGTGTGATGGAAGACGGCACCGGCCTG
GTGGTGGACTTCAGGAACACCGTGATCCTCGCCACCAGCAACGTCGGCGCCGAACTGCTGCTGGACAGCCCGGCCGAACA
GGTCGCCACCCCGGCCTTCGACGAGCGCCTGCGCAAAGTCTTGCTGCAAACCTTCCGCCCGGCGTTCCTCGCGCGCATGA
CCGTGGTGCCTTACCGGCCGCTGGAGGAAGCCACCCTGGAAGGCATCGTCGTGGCCAAGCTGGAAAAACTGCGGGAACGC
TACAAGGCCGCTACCGGCAAACAGTTCGACTTCGACCCGGCCATCGTCAAGGCCGTGCTCGCCAAGTGCAGCGCGGCGGG
CGCGCGGGATATCGAGAACGTGCTGATGGCGCAGGTGACGGGGAAGTTGGCGGAGTGGGTACTCGAATGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (611-775)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (781-848)

• AAA lid domain (AAA_lid_9) (360-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (21-71)

• ATPase family associated with various cellular activities (AAA) (AAA) (220-332)

3D structure

• AlphaFold DB: A0A0H2ZBC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	37.166	100	0.377