Detailed information NTG0836796

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: U7118_RS21860
• Genome accession: NZ_CP141283
• Coordinates: 4064500..4065582 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain DKU_09
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4059500..4070582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U7118_RS21835 (U7118_21835)	cysE	4059605..4060258 (-)	654	WP_014478618.1	serine O-acetyltransferase	-
U7118_RS21840 (U7118_21840)	gltX	4060560..4062011 (-)	1452	WP_014478617.1	glutamate--tRNA ligase	-
U7118_RS21845 (U7118_21845)	ispF	4062102..4062578 (-)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
U7118_RS21850 (U7118_21850)	ispD	4062571..4063269 (-)	699	WP_014478616.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
U7118_RS21855 (U7118_21855)	yacL	4063284..4064384 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
U7118_RS21860 (U7118_21860)	disA	4064500..4065582 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
U7118_RS21865 (U7118_21865)	radA/sms	4065586..4066962 (-)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
U7118_RS21870 (U7118_21870)	clpC	4067054..4069486 (-)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
U7118_RS21875 (U7118_21875)	mcsB	4069483..4070574 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=836796 U7118_RS21860 WP_003225736.1 4064500..4065582(-) (disA) [Bacillus subtilis strain DKU_09]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=836796 U7118_RS21860 WP_003225736.1 4064500..4065582(-) (disA) [Bacillus subtilis strain DKU_09]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1