Detailed information NTG0083624

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: OO845_RS12795
• Genome accession: NZ_AP026937
• Coordinates: 2649034..2650059 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain EC20-4B-2
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 2644034..2655059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OO845_RS12785 (EC204B2_24290)	rpmE	2646265..2646477 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
OO845_RS12790 (EC204B2_24300)	priA	2646680..2648878 (+)	2199	WP_001315935.1	primosomal protein N'	Machinery gene
OO845_RS12795 (EC204B2_24310)	cytR	2649034..2650059 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
OO845_RS12800 (EC204B2_24320)	ftsN	2650151..2651110 (+)	960	WP_000068834.1	cell division protein FtsN	-
OO845_RS12805 (EC204B2_24330)	hslV	2651203..2651733 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
OO845_RS12810 (EC204B2_24340)	hslU	2651743..2653074 (+)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
OO845_RS12815 (EC204B2_24350)	menA	2653141..2654067 (+)	927	WP_001307494.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
OO845_RS12820 (EC204B2_24360)	rraA	2654160..2654645 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
OO845_RS12825 (EC204B2_24370)	zapB	2654730..2654975 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=83624 OO845_RS12795 WP_000644904.1 2649034..2650059(+) (cytR) [Escherichia coli strain EC20-4B-2]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=83624 OO845_RS12795 WP_000644904.1 2649034..2650059(+) (cytR) [Escherichia coli strain EC20-4B-2]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAACCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGCTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCACTGTGTCACTATCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628