Detailed information
Bioinformatically predicted
Overview
| Name | nucA/comI | Type | Machinery gene |
| Locus tag | QNH21_RS08745 | Genome accession | NZ_CP126090 |
| Coordinates | 1752973..1753353 (+) | Length | 126 a.a. |
| NCBI ID | WP_243837381.1 | Uniprot ID | - |
| Organism | Bacillus safensis strain CEW AP102 | ||
| Function | cleavage of dsDNA into ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1687568..1757464 | 1752973..1753353 | within | 0 |
Gene organization within MGE regions
Location: 1687568..1757464
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QNH21_RS08385 (QNH21_08385) | - | 1687568..1688317 (+) | 750 | WP_283860085.1 | poly-gamma-glutamate hydrolase family protein | - |
| QNH21_RS08390 (QNH21_08390) | - | 1688479..1689627 (+) | 1149 | WP_024427032.1 | Rap family tetratricopeptide repeat protein | - |
| QNH21_RS08395 (QNH21_08395) | - | 1689717..1691042 (-) | 1326 | WP_056766528.1 | S8 family peptidase | - |
| QNH21_RS08400 (QNH21_08400) | - | 1691627..1692361 (+) | 735 | WP_283860086.1 | poly-gamma-glutamate hydrolase family protein | - |
| QNH21_RS08405 (QNH21_08405) | - | 1692438..1692887 (+) | 450 | WP_268414401.1 | OsmC family protein | - |
| QNH21_RS08410 (QNH21_08410) | - | 1692934..1693302 (-) | 369 | WP_024424093.1 | multidrug efflux SMR transporter | - |
| QNH21_RS08415 (QNH21_08415) | - | 1693318..1693635 (-) | 318 | WP_024424092.1 | multidrug efflux SMR transporter | - |
| QNH21_RS08420 (QNH21_08420) | - | 1693638..1693898 (-) | 261 | WP_249117528.1 | hypothetical protein | - |
| QNH21_RS08425 (QNH21_08425) | - | 1693911..1694156 (-) | 246 | WP_255290955.1 | helix-turn-helix domain-containing protein | - |
| QNH21_RS08430 (QNH21_08430) | - | 1694292..1694555 (-) | 264 | WP_025093279.1 | hypothetical protein | - |
| QNH21_RS08435 (QNH21_08435) | - | 1694660..1695061 (+) | 402 | WP_034623557.1 | YmaF family protein | - |
| QNH21_RS08440 (QNH21_08440) | miaA | 1695132..1696088 (+) | 957 | WP_197172853.1 | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA | - |
| QNH21_RS08445 (QNH21_08445) | hfq | 1696114..1696335 (+) | 222 | WP_024424088.1 | RNA chaperone Hfq | - |
| QNH21_RS08450 (QNH21_08450) | - | 1696498..1696818 (+) | 321 | WP_024424087.1 | YmzC family protein | - |
| QNH21_RS08455 (QNH21_08455) | - | 1696898..1697110 (+) | 213 | WP_003212415.1 | hypothetical protein | - |
| QNH21_RS08460 (QNH21_08460) | nrdI | 1697376..1697768 (+) | 393 | WP_008360380.1 | class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI | - |
| QNH21_RS08465 (QNH21_08465) | nrdE | 1697728..1699830 (+) | 2103 | WP_024424086.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| QNH21_RS08470 (QNH21_08470) | nrdF | 1699848..1700822 (+) | 975 | WP_283860087.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| QNH21_RS08475 (QNH21_08475) | - | 1700917..1701534 (+) | 618 | WP_024424084.1 | hypothetical protein | - |
| QNH21_RS08480 (QNH21_08480) | - | 1701602..1702360 (-) | 759 | WP_024427042.1 | N-acetylmuramoyl-L-alanine amidase | - |
| QNH21_RS08485 (QNH21_08485) | spoVK | 1702681..1703640 (+) | 960 | WP_024424083.1 | stage V sporulation protein K | - |
| QNH21_RS08490 (QNH21_08490) | hflX | 1703762..1705033 (+) | 1272 | WP_283860088.1 | GTPase HflX | - |
| QNH21_RS08495 (QNH21_08495) | - | 1705040..1706320 (+) | 1281 | WP_283860089.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| QNH21_RS08500 (QNH21_08500) | - | 1706412..1706822 (+) | 411 | WP_283860090.1 | MerR family transcriptional regulator | - |
| QNH21_RS08505 (QNH21_08505) | glnA | 1706883..1708217 (+) | 1335 | WP_025093273.1 | type I glutamate--ammonia ligase | - |
| QNH21_RS08510 (QNH21_08510) | - | 1708263..1708454 (+) | 192 | WP_197172854.1 | hypothetical protein | - |
| QNH21_RS08515 (QNH21_08515) | - | 1708574..1708678 (+) | 105 | WP_235183637.1 | hypothetical protein | - |
| QNH21_RS08520 (QNH21_08520) | - | 1708759..1709613 (+) | 855 | WP_034623549.1 | hypothetical protein | - |
| QNH21_RS08525 (QNH21_08525) | - | 1709658..1710039 (+) | 382 | Protein_1630 | ArpU family phage packaging/lysis transcriptional regulator | - |
| QNH21_RS08530 (QNH21_08530) | - | 1710118..1711827 (+) | 1710 | Protein_1631 | T7SS effector LXG polymorphic toxin | - |
| QNH21_RS08535 (QNH21_08535) | - | 1711840..1712244 (+) | 405 | WP_283860091.1 | hypothetical protein | - |
| QNH21_RS08540 (QNH21_08540) | - | 1712726..1712905 (+) | 180 | WP_056702470.1 | hypothetical protein | - |
| QNH21_RS08545 (QNH21_08545) | - | 1712997..1713341 (+) | 345 | WP_135031713.1 | structural protein | - |
| QNH21_RS08550 (QNH21_08550) | - | 1713397..1713603 (+) | 207 | WP_235183636.1 | hypothetical protein | - |
| QNH21_RS08555 (QNH21_08555) | - | 1713925..1714359 (+) | 435 | WP_034623546.1 | hypothetical protein | - |
| QNH21_RS19285 | terS | 1715164..1716011 (+) | 848 | Protein_1637 | phage terminase small subunit | - |
| QNH21_RS08575 (QNH21_08575) | - | 1716020..1717327 (+) | 1308 | WP_283860148.1 | PBSX family phage terminase large subunit | - |
| QNH21_RS08580 (QNH21_08580) | - | 1717324..1718853 (+) | 1530 | WP_034623543.1 | phage portal protein | - |
| QNH21_RS08585 (QNH21_08585) | - | 1718850..1719766 (+) | 917 | Protein_1640 | phage minor head protein | - |
| QNH21_RS08590 (QNH21_08590) | - | 1719808..1720437 (+) | 630 | WP_034623542.1 | hypothetical protein | - |
| QNH21_RS08595 (QNH21_08595) | - | 1720471..1720731 (+) | 261 | Protein_1642 | XkdF-like putative serine protease domain-containing protein | - |
| QNH21_RS08600 (QNH21_08600) | - | 1720752..1720910 (-) | 159 | Protein_1643 | BhlA/UviB family holin-like peptide | - |
| QNH21_RS08605 (QNH21_08605) | - | 1720981..1721862 (+) | 882 | WP_347343018.1 | N-acetylmuramoyl-L-alanine amidase | - |
| QNH21_RS08610 (QNH21_08610) | - | 1722004..1724277 (-) | 2274 | WP_034623540.1 | S8 family peptidase | - |
| QNH21_RS08615 (QNH21_08615) | - | 1724292..1725395 (-) | 1104 | WP_034623539.1 | ATP-binding protein | - |
| QNH21_RS08620 (QNH21_08620) | - | 1725888..1726040 (+) | 153 | WP_235183634.1 | DUF4325 domain-containing protein | - |
| QNH21_RS08625 (QNH21_08625) | - | 1726229..1727080 (-) | 852 | WP_034623537.1 | hypothetical protein | - |
| QNH21_RS08630 (QNH21_08630) | - | 1727295..1728134 (+) | 840 | WP_283860092.1 | SMI1/KNR4 family protein | - |
| QNH21_RS08635 (QNH21_08635) | - | 1728274..1728408 (+) | 135 | WP_283860093.1 | hypothetical protein | - |
| QNH21_RS08640 (QNH21_08640) | - | 1728534..1730459 (+) | 1926 | WP_283860094.1 | T7SS effector LXG polymorphic toxin | - |
| QNH21_RS08645 (QNH21_08645) | - | 1730466..1730942 (+) | 477 | WP_041109174.1 | immunity protein YezG family protein | - |
| QNH21_RS08650 (QNH21_08650) | - | 1731007..1731468 (-) | 462 | WP_133743787.1 | macro domain-containing protein | - |
| QNH21_RS08655 (QNH21_08655) | - | 1731697..1732278 (+) | 582 | WP_283860095.1 | undecaprenyl-diphosphatase | - |
| QNH21_RS08660 (QNH21_08660) | - | 1732331..1732702 (-) | 372 | WP_283860096.1 | iron chaperone | - |
| QNH21_RS08665 (QNH21_08665) | - | 1733234..1734346 (+) | 1113 | WP_103132502.1 | tetratricopeptide repeat protein | - |
| QNH21_RS08670 (QNH21_08670) | - | 1735075..1735770 (-) | 696 | WP_283860097.1 | YoaK family protein | - |
| QNH21_RS08675 (QNH21_08675) | - | 1735838..1737670 (-) | 1833 | WP_283860098.1 | DNA ligase D | - |
| QNH21_RS08680 (QNH21_08680) | - | 1737786..1738634 (+) | 849 | WP_212048987.1 | Ku protein | - |
| QNH21_RS08685 (QNH21_08685) | - | 1738658..1739101 (-) | 444 | WP_268415793.1 | DUF2188 domain-containing protein | - |
| QNH21_RS08690 (QNH21_08690) | - | 1739262..1739735 (+) | 474 | WP_268415792.1 | VOC family protein | - |
| QNH21_RS08695 (QNH21_08695) | - | 1739784..1740197 (+) | 414 | WP_034283385.1 | Rrf2 family transcriptional regulator | - |
| QNH21_RS08700 (QNH21_08700) | - | 1740298..1741149 (+) | 852 | WP_283860099.1 | SDR family oxidoreductase | - |
| QNH21_RS08705 (QNH21_08705) | - | 1741304..1742212 (+) | 909 | WP_087978135.1 | DMT family transporter | - |
| QNH21_RS08710 (QNH21_08710) | - | 1742225..1742416 (-) | 192 | WP_025093255.1 | hypothetical protein | - |
| QNH21_RS08715 (QNH21_08715) | - | 1742527..1744743 (+) | 2217 | WP_213405081.1 | RNA ligase | - |
| QNH21_RS08720 (QNH21_08720) | - | 1744809..1745519 (+) | 711 | WP_024425121.1 | DUF421 domain-containing protein | - |
| QNH21_RS08725 (QNH21_08725) | - | 1745747..1746325 (+) | 579 | WP_041109214.1 | TetR/AcrR family transcriptional regulator | - |
| QNH21_RS08730 (QNH21_08730) | - | 1746348..1749491 (+) | 3144 | WP_283860100.1 | bifunctional cytochrome P450/NADPH--P450 reductase | - |
| QNH21_RS08735 (QNH21_08735) | - | 1749686..1750594 (+) | 909 | WP_133743783.1 | trypsin-like serine protease | - |
| QNH21_RS08740 (QNH21_08740) | - | 1750741..1752747 (+) | 2007 | WP_198457286.1 | glycosyltransferase family 39 protein | - |
| QNH21_RS08745 (QNH21_08745) | nucA/comI | 1752973..1753353 (+) | 381 | WP_243837381.1 | NucA/NucB deoxyribonuclease domain-containing protein | Machinery gene |
| QNH21_RS08750 (QNH21_08750) | - | 1753498..1754346 (+) | 849 | WP_073205715.1 | STAS domain-containing protein | - |
| QNH21_RS08755 (QNH21_08755) | - | 1754379..1754921 (-) | 543 | WP_122631360.1 | IseA DL-endopeptidase inhibitor family protein | - |
| QNH21_RS08760 (QNH21_08760) | - | 1755216..1755533 (+) | 318 | WP_283860101.1 | hypothetical protein | - |
| QNH21_RS08765 (QNH21_08765) | lexA | 1755709..1756329 (-) | 621 | WP_024425129.1 | transcriptional repressor LexA | - |
| QNH21_RS08770 (QNH21_08770) | yneA | 1756488..1756799 (+) | 312 | WP_024425130.1 | cell division suppressor protein YneA | - |
| QNH21_RS08775 (QNH21_08775) | - | 1756817..1757464 (+) | 648 | WP_122631359.1 | recombinase family protein | - |
Sequence
Protein
Download Length: 126 a.a. Molecular weight: 13741.44 Da Isoelectric Point: 8.5068
>NTDB_id=835295 QNH21_RS08745 WP_243837381.1 1752973..1753353(+) (nucA/comI) [Bacillus safensis strain CEW AP102]
MGTLLGGFGEKQAAKGADRYDHVVQFPKERYPETGTHIQEAIRKGHSDVCTIDRNGADARRQESLKGIPTKPGFDRDEWP
MAVCLEGGKGASVQYVSPSDNRGAGSWVGHQISGFPDGKRILFIVK
MGTLLGGFGEKQAAKGADRYDHVVQFPKERYPETGTHIQEAIRKGHSDVCTIDRNGADARRQESLKGIPTKPGFDRDEWP
MAVCLEGGKGASVQYVSPSDNRGAGSWVGHQISGFPDGKRILFIVK
Nucleotide
Download Length: 381 bp
>NTDB_id=835295 QNH21_RS08745 WP_243837381.1 1752973..1753353(+) (nucA/comI) [Bacillus safensis strain CEW AP102]
ATGGGCACGTTGTTAGGTGGATTTGGAGAGAAGCAGGCAGCAAAAGGGGCTGATCGATATGATCATGTCGTTCAATTTCC
AAAGGAAAGGTACCCTGAAACAGGCACTCATATTCAAGAAGCCATTCGAAAAGGGCATTCAGATGTGTGTACCATTGACC
GAAATGGAGCAGATGCCCGCAGGCAAGAATCATTAAAAGGAATTCCGACAAAACCTGGCTTTGACCGGGATGAATGGCCA
ATGGCGGTTTGTCTTGAGGGAGGAAAAGGCGCAAGCGTACAATATGTCAGTCCATCTGATAATAGGGGAGCAGGCTCATG
GGTCGGGCATCAAATCAGCGGGTTTCCTGATGGGAAAAGAATATTATTCATTGTGAAATAA
ATGGGCACGTTGTTAGGTGGATTTGGAGAGAAGCAGGCAGCAAAAGGGGCTGATCGATATGATCATGTCGTTCAATTTCC
AAAGGAAAGGTACCCTGAAACAGGCACTCATATTCAAGAAGCCATTCGAAAAGGGCATTCAGATGTGTGTACCATTGACC
GAAATGGAGCAGATGCCCGCAGGCAAGAATCATTAAAAGGAATTCCGACAAAACCTGGCTTTGACCGGGATGAATGGCCA
ATGGCGGTTTGTCTTGAGGGAGGAAAAGGCGCAAGCGTACAATATGTCAGTCCATCTGATAATAGGGGAGCAGGCTCATG
GGTCGGGCATCAAATCAGCGGGTTTCCTGATGGGAAAAGAATATTATTCATTGTGAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| nucA/comI | Bacillus subtilis subsp. subtilis str. 168 |
57.983 |
94.444 |
0.548 |