Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8570_RS01770 Genome accession   NZ_AP026932
Coordinates   352634..353266 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 347634..358266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS01745 (PC1528_03420) mvaD 347911..348864 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  R8570_RS01750 (PC1528_03430) - 348851..349858 (+) 1008 WP_000562412.1 phosphomevalonate kinase -
  R8570_RS01755 (PC1528_03440) fni 349842..350852 (+) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8570_RS01760 (PC1528_03450) liaF 350930..351628 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  R8570_RS01765 (PC1528_03460) - 351625..352620 (+) 996 WP_000743680.1 sensor histidine kinase -
  R8570_RS01770 (PC1528_03470) vraR 352634..353266 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  R8570_RS01775 - 353342..354036 (+) 695 Protein_346 DNA alkylation repair protein -
  R8570_RS01780 (PC1528_03500) - 354186..354425 (+) 240 WP_000754502.1 hypothetical protein -
  R8570_RS01785 (PC1528_03510) cbpG 354506..355327 (+) 822 WP_001100136.1 choline-binding protein CbpG -
  R8570_RS01790 cbpF 355346..356368 (+) 1023 Protein_349 choline-binding protein CbpF -
  R8570_RS01795 - 356496..357631 (-) 1136 Protein_350 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=83487 R8570_RS01770 WP_000698434.1 352634..353266(+) (vraR) [Streptococcus pneumoniae strain PZ900701549]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=83487 R8570_RS01770 WP_000698434.1 352634..353266(+) (vraR) [Streptococcus pneumoniae strain PZ900701549]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment